2 Results for "

GS7682

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "GS7682" in MCE Product Catalog:

Cat. No.: HY-161877
CAS No.: 2694736-39-3
Target:  

RSV

Research Areas:  

Infection

GS-7682 is an antiviral compound. GS-7682 has inhibitory activity against pneumoviruses and picornaviruses. GS-7682 can be used in the study of respiratory diseases such as asthma and chronic obstructive pulmonary disease .
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Cat. No.: HY-185215
CAS No.: 1770840-57-7
Target:  

DNA/RNA Synthesis RSV

Research Areas:  

Infection

GS-646089 is a broad-spectrum antiviral nucleoside analog that exhibits significant inhibitory activity against respiratory syncytial virus (RSV), human metapneumovirus (hMPV), rhinovirus (enterovirus) and enteroviruses. The IC50 of GS-646089 targeting RNA-dependent RNA polymerase (RdRp) ranges from 43 to 46 nM. GS-646089 blocks viral replication by being converted into a triphosphate metabolite intracellularly, which competes with ATP for incorporation into nascent RNA strands and acts as an immediate chain terminator. GS-646089 is the parent compound of the double prodrug GS-7682 (HY-161877), and is used in studies of acute respiratory viral infections and infections caused by related pathogens .
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