2. Anti-infection
  3. RSV
  4. GS-7682

GS-7682 is an antiviral compound. GS-7682 has inhibitory activity against pneumoviruses and picornaviruses. GS-7682 can be used in the study of respiratory diseases such as asthma and chronic obstructive pulmonary disease.

For research use only. We do not sell to patients.

GS-7682

GS-7682 Chemical Structure

CAS No. : 2694736-39-3

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GS-7682 Related Antibodies

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Description

GS-7682 is an antiviral compound. GS-7682 has inhibitory activity against pneumoviruses and picornaviruses. GS-7682 can be used in the study of respiratory diseases such as asthma and chronic obstructive pulmonary disease[1].

Cellular Effect
Cell Line Type Value Description References
A549 CC50
21.1 μM
Compound: 1; GS-7682
Cytotoxicity against human A549 cells expressing hACE2 incubated for 28 hrs by Cell Titer Glo assay
Cytotoxicity against human A549 cells expressing hACE2 incubated for 28 hrs by Cell Titer Glo assay
[PMID: 39018526]
Epithelial cell CC50
8.3 μM
Compound: 1; GS-7682
Cytotoxicity against Normal human bronchial epithelial cells
Cytotoxicity against Normal human bronchial epithelial cells
[PMID: 39018526]
H1-HeLa CC50
22.2 μM
Compound: 1; GS-7682
Cytotoxicity against human H1-HeLa cells incubated for 96 hrs by Cell Titer Glo assay
Cytotoxicity against human H1-HeLa cells incubated for 96 hrs by Cell Titer Glo assay
[PMID: 39018526]
HEp-2 CC50
22.7 μM
Compound: 1; GS-7682
Cytotoxicity against human Hep-2 cells incubated for 4 to 5 days by Cell Titer Glo assay
Cytotoxicity against human Hep-2 cells incubated for 4 to 5 days by Cell Titer Glo assay
[PMID: 39018526]
LLC-MK2 CC50
> 2 μM
Compound: 1; GS-7682
Cytotoxicity against rhesus monkey LLC-MK2 cells incubated for 5 days by MTS assay
Cytotoxicity against rhesus monkey LLC-MK2 cells incubated for 5 days by MTS assay
[PMID: 39018526]
MDCK CC50
> 2 μM
Compound: 1; GS-7682
Cytotoxicity against MDCK cells by MTS assay
Cytotoxicity against MDCK cells by MTS assay
[PMID: 39018526]
MT4 CC50
3.24 μM
Compound: 1; GS-7682
Cytotoxicity against human MT4 cells incubated for 5 days by Cell Titer Glo assay
Cytotoxicity against human MT4 cells incubated for 5 days by Cell Titer Glo assay
[PMID: 39018526]
RD CC50
> 2 μM
Compound: 1; GS-7682
Cytotoxicity against human RD cells by MTS assay
Cytotoxicity against human RD cells by MTS assay
[PMID: 39018526]
Molecular Weight

672.62

Formula

C30H37N6O10P
CAS No.
SMILES

O=[P@](N[C@@H](C)C(OC)=O)(OC1=CC=CC=C1)OC[C@]2(C#N)[C@@H](OC(C(C)C)=O)[C@@H](OC(C(C)C)=O)[C@H](C3=CC=C4N3N=CN=C4N)O2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GS-7682 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GS-76822694736-39-3GS7682GS 7682RSVRespiratory syncytial virusAcute respiratory viral infectionshuman metapneumovirushuman rhinovirusInhibitorinhibitorinhibit

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