6 Results for "

Hs683

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Hs683" in MCE Product Catalog:

Cat. No.: HY-125848
CAS No.: 62025-49-4
Purity:  99.95%
Ginsenoside F2 is an orally active bioactive compound that participates in the regulation of metabolism and inflammation. Ginsenoside F2 promotes the phosphorylation of AMPK and ACC, binds to PPARγ, inhibits the phosphorylation of MAPK, activates the PI3K/AKT/GSK-3β pathway, reduces GLRX expression, and regulates lipid metabolism. Ginsenoside F2 reduces ROS production and MDA levels, restores SOD activity in cells, and alleviates oxidative stress. Ginsenoside F2 induces cell apoptosis (Apoptosis) and increases the number of cleaved caspase-3-positive cells. Ginsenoside F2 reduces body weight gain, adipose tissue weight and serum lipid levels in obese mice, and activates the hepatic AMPK signaling pathway and the expression of antioxidant enzymes. Ginsenoside F2 alleviates atopic dermatitis in mice by inhibiting inflammation and reshaping the gut microbiota . Ginsenoside F2 is applicable to research related to insulin resistance, obesity, atopic dermatitis, liver cancer, glioblastoma and glioma .
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Cat. No.: HY-161303
CAS No.: 2923208-52-8
Research Areas:  

Cancer

ZNF207-IN-1 is an orally active and brain-penetrant ZNF207 inhibitor with a target KD of 67 nM. ZNF207-IN-1 binds directly to ZNF207, downregulates stem-related genes and weakens glioma cell stemness. ZNF207-IN-1 hinders tumorigenesis and migration and promotes apoptosis. ZNF207-IN-1 can be used for the research of glioma[1].
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Cat. No.: HY-137052
CAS No.: 15069-99-5
Synonyms: N-Methyllycorine iodide
Target:  

Drug Derivative

Research Areas:  

Cancer

Lycorine methiodide (N-Methyllycorine iodide) is a derivative of Lycorine (HY-N0288). Lycorine methiodide exhibits no significant in vitro antitumor activity against A549, OE21, Hs683, U373, SKMEL, and B16F10 cell lines, with all IC50 values greater than 10 μM .
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Cat. No.: HY-N7158
CAS No.: 154801-30-6
Elasticamide is a natural compound isolated from Ficus elastica Roxb. Elasticamide inhibits the cell growth in the U373n, with the IC50 of 88 μM .
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Cat. No.: HY-153509
CAS No.: 1392810-44-4
Target:  

Sirtuin

Research Areas:  

Cancer

Sirtuin-IN-1 (Compound 18) is a SIRT1/2 inhibitor (IC50s: 6.2 μM and 4.2μM for SIRT1 and SIRT2, respectively). Sirtuin-IN-1 induces G1 cell cycle arrest. Sirtuin-IN-1 exhibits potent anti-cancer activity against glioma .
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Cat. No.: HY-126700
CAS No.: 39022-38-3
Sphaeropsidin B is a pimarane diterpene and phytotoxin. Sphaeropsidin B can be found in Diplodia cupressi and Diplodia corticola. Sphaeropsidin B induces phytotoxic effects in plants. Sphaeropsidin B can be used for the research of plant injury-related research areas .
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