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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

Huh7 human hepatocellular carcinoma cells

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153492A
    Olpasiran sodium

    AMG 890 sodium; ARC-LPA sodium

    		 Small Interfering RNA (siRNA) Inflammation/Immunology
    Olpasiran (AMG 890, ARC-LPA) sodium is an N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted siRNA. Olpasiran sodium directly inhibits LPA messenger RNA translation in hepatocytes and potently reduce Lp(a) concentration. Olpasiran sodium can be used for the research of cardiovascular disease, such as atherosclerosis .
    Olpasiran sodium
  • HY-181873
    Rapamycin-butyl ester

    Sirolimus-butyl ester

    		 Drug Derivative Cancer
    Rapamycin-butyl ester (Sirolimus-butyl ester) (Compound 9) is a derivative of Rapamycin (HY-10219). Rapamycin-butyl ester exhibits antiproliferative effects against liver cancer cells and renal cancer cells. Rapamycin-butyl ester can be used in research related to liver cancer and renal cancer .
    Rapamycin-butyl ester
  • HY-181692
    PROTAC RNF4 degrader-1

    		PROTACs Epigenetic Reader Domain E1/E2/E3 Enzyme Apoptosis Cancer
    PROTAC RNF4 degrader-1 is a RNF4 PROTAC degrader (Kd = 64.5 nM) that degrades RNF4 via the ubiquitin-proteasome system. PROTAC RNF4 degrader-1 induces DNA damage, apoptosis, and exhibits antiproliferative activity in cancer cells. PROTAC RNF4 degrader-1 displays antitumor activity with no obvious side effects in mouse models. PROTAC RNF4 degrader-1 is applicable to the research of hepatocellular carcinoma .
    PROTAC RNF4 degrader-1
  • HY-183271
    Tubulin-IN-67

    		Microtubule/Tubulin Cancer
    Tubulin-IN-67 is a tubulin inhibitor. Tubulin-IN-67 binds to the colchicine-binding site of tubulin, inhibiting tubulin polymerization. Tubulin-IN-67 arrests cancer cell cycle at the G2/M phase and triggers apoptosis in cancer cells. Tubulin-IN-67 can be used for the research of hepatocellular carcinoma, cervical carcinoma, breast carcinoma .
    Tubulin-IN-67
  • HY-183920
    LC-1310

    		CMV p97 Infection
    LC-1310 is an antiviral agent that targets and inhibits p97, and it suppresses the in vitro replication of human cytomegalovirus (HCMV) with an EC50 value of 0.3 μM. LC-1310 targets the D2 ATP-binding site of p97, downregulates the expression of early viral proteins, thereby blocking the transcription and proliferation of early viral genes. LC-1310 can be used for research on human cytomegalovirus infection .
    LC-1310

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