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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Lipase Inhibition
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Lipase Inhibition" in MCE Product Catalog:
3
3 Cited Publications
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JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.
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Triterpenes Terpenoids Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology
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MAGL-IN-4 is an orally active, selective and reversible monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 6.2 nM. MAGL-IN-4 can penetrate the blood-brain barrier (BBB). MAGL-IN-4 enhances endocannabinoid signaling mostly by the increase in the level of 2-AG via selective MAGL inhibition in the brain .
Cat. No.: HY-N16617
CAS No.: 91095-81-7
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Cat. No.: HY-N4298
CAS No.: 102067-92-5
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Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Inflammation/Immunology Theaceae
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Cat. No.: HY-N8989
CAS No.: 201012-14-8
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Natural Products Metabolic Disease Plants Compositae Disease Research Fields Erythrina sigmoidea Hua
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Cat. No.: HY-114754
CAS No.: 1998101-23-7
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BemPPOX is an orally active, potent dog gastric lipase (DGL) inhibitor with Xl50 (the inhibitor molar excess leading to 50% lipase inhibition) of 0.5. BemPPOX is also a good inhibitor of GPLRP2 (xl50=0.64). BemPPOX efficiently regulates the gastrointestinal lipolysis and slows down the overall lipolysis process in rats. BemPPOX has the potential for obesity research .
Cat. No.: HY-187713
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α-Glucosidase-IN-122 is an inhibitor of α-glucosidase (α-Glucosidase). α-Glucosidase-IN-122 regulates glucose and lipid metabolism through multiple pathways, including inhibition of α-glucosidase and lipase, and exertion of antioxidant activity, and enhances glucose consumption in insulin-resistant HepG2 cells. α-Glucosidase-IN-122 can be used in the research of type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
