1 Result for "

MK256

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MK256" in MCE Product Catalog:

Cat. No.: HY-183423
CAS No.: 2271348-04-8
Target:  

CDK STAT Bcl-2 Family CCR

Research Areas:  

Cancer

MK256 is an orally active, selective CDK8 inhibitor and CDK19/cyclin C inhibitor with IC50 values of 2.5 nM and 3.3 nM, respectively. MK256 downregulates phosphorylated STAT1 (S727), STAT5 (S726), MCL-1 mRNA and CCL2 mRNA. MK256 exhibits anti-tumor activity in acute myeloid leukemia. MK256 can be used for the research of acute myeloid leukemia .
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