250 Results for "

Marine

" in MedChemExpress (MCE) Product Catalog:
Products (250)

250 Results for "Marine" in MCE Product Catalog:

24
24 Publications Verification
製品番号: HY-N6785A
CAS 番号: 209266-80-8
Target:  

Phosphatase Apoptosis

研究分野:  

Neurological Disease Cancer

Okadaic acid sodium, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid (sodium) has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid sodium increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid sodium induces tau phosphorylation .
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24
24 Publications Verification
製品番号: HY-115760
CAS 番号: 175522-42-6
Target:  

Phosphatase

研究分野:  

Neurological Disease Cancer

Okadaic acid ammonium salt, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid ammonium salt has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid ammonium salt increases of phosphorylation of a number of proteins by inhibiting PP, and acts as a tumor promoter. Okadaic acid ammonium salt induces tau phosphorylation .
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24
24 Publications Verification
製品番号: HY-N6785
CAS 番号: 78111-17-8
Okadaic acid, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid induces tau phosphorylation .
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14
14 Cited Publications
製品番号: HY-N2302
CAS 番号: 3351-86-8
別名: all-trans-Fucoxanthin
Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities .
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9
9 Cited Publications
製品番号: HY-P0027
CAS 番号: 102396-24-7
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .
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6
6 Cited Publications
製品番号: HY-101848
CAS 番号: 76343-94-7
純度:  ≥98.0%
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .
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3
3 Cited Publications
製品番号: HY-14602
CAS 番号: 3687-18-1
純度:  ≥98.0%
別名: Homotaurine; 3-Amino-1-propanesulfonic acid
Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects .
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2
2 Cited Publications
製品番号: HY-119500
CAS 番号: 71678-03-0
純度:  ≥98.0%
Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Ilimaquinone can induce vesiculation of the Golgi apparatus . Ilimaquinone exerts anti-HIV, anti-microbial, anti-inflammatory, and effects .
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2
2 Cited Publications
製品番号: HY-133968
CAS 番号: 474-63-5
純度:  99.48%
別名: Ostreasterol
24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .
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1
1 Cited Publications
製品番号: HY-N7819
CAS 番号: 1921-70-6
別名: Norphytane
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .
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1
1 Cited Publications
製品番号: HY-105055
CAS 番号: 77327-05-0
純度:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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1
1 Cited Publications
製品番号: HY-163001
CAS 番号: 2408008-21-7
Category:  

Microorganisms

Target:  

Autophagy p62 Atg8/LC3

Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models .
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1
1 Cited Publications
製品番号: HY-W016622
CAS 番号: 28940-11-6
別名: 7-Methyl-2H-1,5-benzodioxepin-3(4H)-one
Watermelon ketone (7-Methyl-2H-1,5-benzodioxepin-3(4H)-one) is a compound with a fresh marine scent .
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1
1 Cited Publications
製品番号: HY-N9251
CAS 番号: 90821-99-1
Cyclo(Ile-Ala) is found in marine actinomycete 11014 I. .
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1
1 Cited Publications
製品番号: HY-113604
CAS 番号: 10245-81-5
純度:  99.63%
Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer .
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1
1 Cited Publications
製品番号: HY-N1307
CAS 番号: 145382-68-9
Sideroxylonal A is an effective marine antifouling agent isolated from Eucalyptus jensenii. Sideroxylonal A has antibacterial activity against the Gram-positive bacteria Staphylococcus aureus and Bacilus subtilis .
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1
1 Cited Publications
製品番号: HY-W012479
CAS 番号: 153-94-6
別名: D-Tryptophan
H-D-Trp-OH (D-Tryptophan) is the D-isomer of tryptophan, which is occasionally found in natural peptides, such as marine toxin peptides. H-D-Trp-OH can increase intestinal microbial diversity and counteract the inhibitory effect of allergic airway inflammation on intestinal microbial diversity .
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1
1 Cited Publications
製品番号: HY-19827
CAS 番号: 28656-91-9
別名: (+)-Aeroplysinin-1
Aeroplysinin 1 ((+)-Aeroplysinin-1), a secondary metabolite isolated from marine sponges, shows potent antibiotic effects on Gram-positive bacteria and exerts antiviral activity against HIV-1 (IC50=14.6 μM). Aeroplysinin 1 has anti-inflammatory, anti-angiogenic and anti-tumor activities. Aeroplysinin 1 induces apoptosis in endothelial cells .
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1
1 Cited Publications
製品番号: HY-P2915
CAS 番号: 9029-47-4
研究分野:  

Infection

Protocatechuate 3,4-dioxygenase is a dioxygenase. Protocatechuate 3,4-dioxygenase belongs to the non-heme iron dioxygenase class. Protocatechuate 3,4-dioxygenase catalyzes the cleavage of the aromatic ring of 3,4-dihydroxybenzoate, attaching two atoms of molecular oxygen to the compound to generate β-carboxy-cis,cis-muconate. Protocatechuate 3,4-dioxygenase is a key enzyme in the β-ketoadipic acid pathway. It is found in marine bacteria associated with Roseobacter. Protocatechuate 3,4-dioxygenase can be isolated from Pseudomonas aeruginosa .
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1
1 Cited Publications
製品番号: HY-W097570
CAS 番号: 38006-08-5
Target:  

Antibiotic Bacterial

研究分野:  

Infection Neurological Disease

Sulfamonomethoxine sodium is an orally active broad-spectrum synthetic sulfonamide antibiotic that inhibits dihydropteroate synthetase. Sulfamonomethoxine sodium increases blood glucose levels, induces anxiety-related activities and impairs spatial learning and memory. Sulfamonomethoxine sodium can be used for the research of anxiety, spatial memory impairment, colisepticemia, salmonellosis, and staphylococcus infection .
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