15 Results for "

Microbial transformation

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "Microbial transformation" in MCE Product Catalog:

2
2 Cited Publications
製品番号: HY-126490
CAS 番号: 11006-33-0
純度:  ≥95.0%
Phleomycin is a copper-dependent DNA damaging agent and antibiotic with antitumor activity. Phleomycin binds to DNA and produces ROS in the presence of reducing agents (such as dithiothreitol and glutathione), inducing single-strand and double-strand breaks in DNA. Phleomycin can induce cell apoptosis or mutation and is widely used in cancer inhibition, microbial genetic transformation (as a screening marker to improve fungal transformation efficiency) and DNA repair mechanism research .
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1
1 Cited Publications
製品番号: HY-N13015
CAS 番号: 34199-21-8
Quercetin 5-O-β-D-glucopyranoside is a glycosylated flavonoid metabolite and flavonoid compound. Quercetin 5-O-β-D-glucopyranoside can be produced by microbial transformation of Quercetin (HY-18085) via Mucor hiemalis. Quercetin 5-O-β-D-glucopyranoside can be used in studies related to benign prostatic hyperplasia .
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1
1 Cited Publications
製品番号: HY-21509
CAS 番号: 2442-31-1
Target:  

NADPH Oxidase

研究分野:  

Others

8-Hydroxycoumarin is an intermediate in the microbial transformation of quinolone .
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製品番号: HY-N3097
CAS 番号: 18836-52-7
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .
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製品番号: HY-N0881
CAS 番号: 4026-95-3
別名: Deacetylcinobufagin
Desacetylcinobufagin is a natural compound used for microbial transformation.
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製品番号: HY-W278566
CAS 番号: 3086-91-7
Saluamine is an important N-dealkylated metabolite of Furosemide (HY-B0135) that is produced by microbial transformation and bile metabolism. Saluamine is a contaminant .
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製品番号: HY-162836
CAS 番号: 13929-35-6
別名: 4-O-(Carboxymethyl)-Rifamycin
Target:  

Antibiotic Bacterial

研究分野:  

Infection

Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .
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製品番号: HY-N15194A
Target:  

Bacterial Apoptosis

研究分野:  

Infection Cancer

Inostamycin A sodium is an inhibitor of cytidine-5'-diphosphate-1,2-diacyl-sn-glycerol (CDP-DG):inositol transferase. Inostamycin A sodium reduces phosphatidylinositol turnover, and inhibits cell proliferation and transformation. Inostamycin A sodium inhibits cancer cell proliferation, induces apoptosis, and prevents tumor recurrence. Inostamycin A sodium exhibits antibacterial activity. Inostamycin A sodium is applicable to research related to infection and cancer .
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製品番号: HY-N12167
CAS 番号: 465-20-3
Category:  

Microorganisms Steroids

Target:  

Others

3-epi-Bufalin (compound 2a) is the microbial transformation product of bufadienolide .
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製品番号: HY-132271
CAS 番号: 23214-93-9
Category:  

天然物 Microorganisms

Target:  

Endogenous Metabolite

Chloramphenicol 1-acetate (Compound Ⅲ) is a microbial transformation product of Chloramphenicol (HY-B0239) by Streptomyces coelicolor. Chloramphenicol 1-acetate is the major product of Chloramphenicol acetyltransferase I (CATI) by regioselective acetylation of C21 hydroxy groups in steroids .
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製品番号: HY-N3097R
CAS 番号: 18836-52-7
Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.
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製品番号: HY-W278566R
CAS 番号: 3086-91-7
Saluamine (Standard) is the analytical standard of Saluamine (HY-W278566). This product is intended for research and analytical applications. Saluamine is an important N-dealkylated metabolite of Furosemide (HY-B0135) that is produced by microbial transformation and bile metabolism .
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製品番号: HY-N15730
CAS 番号: 172608-85-4
3-Hydroxymycophenolic acid (Compound 5) is a microbial transformation product of Mycophenolic acid (HY-B0421) by Cunninghamella echinulata. 3-Hydroxymycophenolic acid has low cytotoxicity against AGS cells and fibroblasts. 3-Hydroxymycophenolic acid can be used for immune-mediated renal diseases research .
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製品番号: HY-N3687
CAS 番号: 202343-57-5
Category:  

天然物 Microorganisms

Target:  

Others

Dasycarpol (compound 2) is a product of microbial transformation of fraxinellone by Aspergillus niger (AS 3.421). Dasycarpol shows moderate cytotoxicity against A549 cells ,with the IC50 of 20 ug/mL .
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製品番号: HY-N17250
CAS 番号: 32751-73-8
Category:  

天然物 Microorganisms

Target:  

Drug Derivative

5-exo-Hydroxyborneol is a hydroxylated monoterpenoid that is a product of microbial transformation of (+)-bornyl acetate by Helminthosporium sativum .
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