39 Results for "

N-Succinimidyl

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "N-Succinimidyl" in MCE Product Catalog:

46
46 Publications Verification
Cat. No.: HY-112847A
Purity:  ≥98.0%
Synonyms: Sulfo-N-Succinimidyl oleate sodium
Target:  

Mitophagy

Research Areas:  

Inflammation/Immunology

Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect .
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11
11 Cited Publications
Cat. No.: HY-D0056
CAS No.: 150206-05-6
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye (Ex=492 nm, Em=517 nm). 5-Carboxyfluorescein diacetate N-succinimidyl ester can label cells by covalently binding to intracellular molecules. 5-Carboxyfluorescein diacetate N-succinimidyl ester is used to track lymphocyte migration and proliferation .
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3
3 Cited Publications
Cat. No.: HY-D0723
CAS No.: 246256-50-8
Synonyms: 5(6)-Carboxytetramethylrhodamine N-Succinimidyl ester
5(6)-TAMRA SE is a fluorescent dye that emits red fluorescence. 5(6)-TAMRA SE binds to oligonucleotides and is used in DNA sequencing. 5(6)-TAMRA SE can be used in cancer research (Ex/Em = 565/580 nm) .
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2
2 Cited Publications
Cat. No.: HY-119523
CAS No.: 23024-29-5
Purity:  ≥97.0%
Synonyms: DSSeb; Sebacic acid bis N-Succinimidyl ester
Research Areas:  

Others

Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides .
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1
1 Cited Publications
Cat. No.: HY-135233
CAS No.: 76931-93-6
Purity:  99.56%
Synonyms: SATA
N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .
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1
1 Cited Publications
Cat. No.: HY-D0049
CAS No.: 150810-69-8
Synonyms: 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-Succinimidyl ester
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .
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1
1 Cited Publications
Cat. No.: HY-128926
CAS No.: 341498-08-6
Purity:  97.65%
Synonyms: N-Succinimidyl 4-(2-pyridyldithio) pentanoate
Target:  

ADC Linkers

Research Areas:  

Cancer

SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate .
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Cat. No.: HY-W011541
CAS No.: 39028-27-8
Synonyms: Iodoacetic acid N-hydroxysuccinimide ester; N-Succinimidyl Iodoacetate
Target:  

ADC Linkers

Research Areas:  

Cancer

SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-D0026
CAS No.: 113721-87-2
Synonyms: 7-Amino-4-methyl-3-coumarinacetic acid N-Succinimidyl ester
AMCA,SE (7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester) is a bright blue fluorescent dye. AMCA,SE reacts with amino groups and is excited by ultraviolet light. AMCA,SE can be used for amine reactive labeling (Ex/Em = 354/440 nm) .
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Cat. No.: HY-W013976
CAS No.: 84271-78-3
Research Areas:  

Others

3-(Acetylthio)propionic acid N-succinimidyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W042558
CAS No.: 69888-86-4
N-Succinimidyl myristate is a biochemical reagent.
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Cat. No.: HY-W012166
CAS No.: 42014-51-7
Synonyms: NHS-Bromoacetate
Research Areas:  

Infection

N-Succinimidyl bromoacetate (NHS-Bromoacetate) is a heterobifunctional crosslinking reagent, mainly used to modify the ɛ-amino group of lysine side chains. By covalently linking its bromoacetyl moiety to the ɛ-amino group of lysine in peptidomimetics, N-Succinimidyl bromoacetate enables their conjugation with thiol-modified nanoparticles via thioether bonds. N-Succinimidyl bromoacetate also performs bromoacetylation modification on carrier proteins, which then forms stable thioether bonds with the thiol groups of cysteine in peptides, thus efficiently preparing soluble peptide-protein conjugates with high substitution ratios. N-Succinimidyl bromoacetate can be used to prepare activated Sepharose derivatives for affinity chromatography, protein affinity labeling reagents, and peptide-protein immunogen conjugates with non-immunogenic linkages. N-Succinimidyl bromoacetate is applicable to studies related to HIV-1 infection and glioblastoma multiforme .
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Cat. No.: HY-W043748
CAS No.: 38862-24-7
Synonyms: N-Succinimidyl acrylate
Research Areas:  

Others

2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a lysine residue modifier and coupling monomer. 2,5-Dioxopyrrolidin-1-yl acrylate covalently modifies the primary amines of lysine residues on monoclonal anti-horseradish peroxidase IgG antibodies, neutralizes positive charges and replaces them with low-affinity acrylate groups. 2,5-Dioxopyrrolidin-1-yl acrylate inhibits the formation of rapid hard coronas on citrate-coated gold nanoparticles, induces antibody unfolding and loss of antigen-binding function, but does not affect the antigen-binding function of antibodies in free solution. 2,5-Dioxopyrrolidin-1-yl acrylate reacts with the ε-amino groups on lysine residues of L-asparaginase, introduces vinyl groups and generates N-hydroxysuccinimide. 2,5-Dioxopyrrolidin-1-yl acrylate regulates the activity of L-asparaginase .
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Cat. No.: HY-78733
CAS No.: 130878-68-1
Research Areas:  

Others

N-Fmoc-L-valine N-succinimidyl ester is a valine derivative .
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Cat. No.: HY-141099
CAS No.: 59156-70-6
Purity:  ≥95.0%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Di(N-succinimidyl)adipate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-D1514
CAS No.: 190714-26-2
NIR-641 N-succinimidyl ester is a fluorescent dye .
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Cat. No.: HY-112847
CAS No.: 135661-44-8
Synonyms: Sulfo-N-Succinimidyl oleate
Target:  

Mitophagy

Research Areas:  

Inflammation/Immunology

Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect .
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Cat. No.: HY-112847B
CAS No.: 1212012-37-7
Synonyms: (E/Z)-Sulfo-N-Succinimidyl oleate sodium
(E/Z)-Sulfosuccinimidyl oleate sodium is the racemate of (E)-Sulfosuccinimidyl oleate sodium and (Z)-Sulfosuccinimidyl oleate sodium. Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long-chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of the mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds to the CD36 receptor on the surface of microglial cells. Sulfosuccinimidyl oleate sodium exhibits anti-inflammatory effects .
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Cat. No.: HY-141385
CAS No.: 57159-62-3
Synonyms: 3-(2-Bromoacetamido)propanoic acid NHS ester
Research Areas:  

Cancer

N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-178293
Research Areas:  

Cancer

N-Succinimidyl 3-maleimidopropionate (Compound MC1) is a Glucuronide-Gemcitabine conjugate. N-Succinimidyl 3-maleimidopropionate can be used to synthesize ADCs (such as cAc10ec-MC1). N-Succinimidyl 3-maleimidopropionate can be used in Hodgkin's lymphoma research .
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