1212012-37-7
Chemical Structure
(E/Z)-Sulfosuccinimidyl oleate sodium
Synonym(s): (E/Z)-Sulfo-N-succinimidyl oleate sodium
- CAS No.: 1212012-37-7
- Formula:C22H36NNaO7S
- Molecular Weight:481.58
InChIKey: FZVVLJSNKVOPRF-RRABGKBLSA-M
SMILES: CCCCCCCC/C=C/CCCCCCCC(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)=O
Biological Activity: (E/Z)-Sulfosuccinimidyl oleate sodium is the racemate of (E)-Sulfosuccinimidyl oleate sodium and (Z)-Sulfosuccinimidyl oleate sodium. Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long-chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of the mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds to the CD36 receptor on the surface of microglial cells. Sulfosuccinimidyl oleate sodium exhibits anti-inflammatory effects[1][2].
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(E/Z)-Sulfosuccinimidyl oleate sodium | (E/Z)-Sulfosuccinimidyl oleate sodium is the racemate of (E)-Sulfosuccinimidyl oleate sodium and (Z)-Sulfosuccinimidyl oleate sodium. Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long-chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of the mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds to the CD36 receptor on the surface of microglial cells. Sulfosuccinimidyl oleate sodium exhibits anti-inflammatory effects. | |||||||||||||||||||||
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- [1]. Dhungana H, et al. Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation. J Neuroinflammation. 2017;14(1):237. Published 2017 Dec 4. [Content Brief]
- [2]. Drahota Z, et al. Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain. Biochem Biophys Res Commun. 2010;391(3):1348-1351. [Content Brief]
