135661-44-8
Chemical Structure
Sulfosuccinimidyl oleate
Synonym(s): Sulfo-N-succinimidyl oleate
- CAS No.: 135661-44-8
- Formula:C22H37NO7S
- Molecular Weight:459.60
IUPAC Name: 1-(oleoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid
InChIKey: LFZDKQJJMZRWMV-KTKRTIGZSA-N
SMILES: O=S(C(C1)C(N(OC(CCCCCCC/C=C\CCCCCCCC)=O)C1=O)=O)(O)=O
Biological Activity: Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect[1][2].
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Sulfosuccinimidyl oleate | Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect. | |||||||||||||||||||||
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- [1]. Dhungana H, et al. Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation. J Neuroinflammation. 2017 Dec 4;14(1):237. [Content Brief]
- [2]. Drahota Z, et al. Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain. Biochem Biophys Res Commun. 2010 Jan 15;391(3):1348-51. [Content Brief]
Keywords
