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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
NAD sodium analog
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "NAD sodium analog" in MCE Product Catalog:
Synonyms: ε-NAD
Research Areas:
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) is a fluorescent analog of NAD. Nicotinamide 1,N6-ethenoadenine dinucleotide can be cleaved by phosphodiesterase I (from C. adamanteus venom) and binds to bovine liver glutamate dehydrogenase. Nicotinamide 1,N6-ethenoadenine dinucleotide can serve as a substrate for G-ADP ribosylation of G proteins catalyzed by bacterial toxins. Nicotinamide 1,N6-ethenoadenine dinucleotide can be used as a fluorescent substrate for the study of ADP ribosylation reactions .
Target:
Research Areas:
Thionicotinamide adenine dinucleotide (Thio-NAD) is a thione-modified analog of the coenzyme nicotinamide adenine dinucleotide (NAD +). Thionicotinamide adenine dinucleotide can replace NAD + in enzymatic reactions and shift the absorption peak to 405 nM, enabling sensitive, real-time kinetic detection of enzyme activity, which is particularly suitable for high-sensitivity diagnostic cyclic detection systems .
Research Areas:
α-NAD (α-Nicotinamide Adenine Dinucleotide) serves as a substrate for reninase, functions as an analog of β-NAD, affects the kinetics of NAD-dependent enzymes, and also plays a critical role as a cofactor in mitochondrial redox reactions .
Cat. No.: HY-131009
Purity: 66.20%
Research Areas:
Fluorescein-NAD + is a fluorescent NAD + analog that can be used in studies related to the detection of ADP-ribosylation reactions. Fluorescein-NAD + enables visualization of ADP-ribose groups, thereby facilitating the detection of ADP-ribosylation reactions. Fluorescein-NAD + serves as a substrate for detecting the auto-ribosylation activity of SIRT6 and the ADP-ribosylation of RhoA by C3larvin toxin .
Synonyms: 3-APAD, 90%; 3-Acetylpyridine NAD, 90%
Cat. No.: HY-164690A
CAS No.: 2600354-60-5
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Nicotinamide-guanine dinucleotide sodium, a NAD sodium (HY-B0445A) analog, is an oxidized forms of nicotinamide guanine dinucleotide. Nicotinamide-guanine dinucleotide sodium serves as coenzymes for alcohol dehydrogenase (ADH) in vitro .
Cat. No.: HY-161712
CAS No.: 2427862-70-0
IMPDH-IN-4 is a derivative of N-pyridinylthiophene carboxamid that exhibits activity against peripheral nerve sheath carcinoma cells. IMPDH-IN-4 is metabolized by NAMPT and NMNAT1 to an adenine dinucleotide (AD) derivative, which is an NAD analog and can inhibit inosine monophosphate dehydrogenase (IMPDH), leading to the accumulation of inosine monophosphate (IMP) in cells. IMPDH-IN-4 has good blood-brain barrier permeability and can be used in the study of central and peripheral nervous system cancers .
Cat. No.: HY-131829
CAS No.: 59587-50-7
Synonyms: 6-AE-NAD+
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N6-(2-Aminoethyl)-NAD+ (6-AE-NAD+) is an adenine-modified NAD analog with coenzyme activity and the property of targeting lactate dehydrogenase (LDH). N6-(2-Aminoethyl)-NAD+ undergoes transient affinity binding with LDH, thereby crosslinking the enzyme monolayer into an integrated electrode. N6-(2-Aminoethyl)-NAD + is a component of the PQQ (HY-100196)-NAD + binary interface, and supports the bioelectrocatalytic oxidation of lactate through PQQ-mediated immobilized NADH oxidation .
Cat. No.: HY-E70238
CAS No.: 126609-61-8
Synonyms: Nicotinamide 2-azidoadenine dinucleotide
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2-Azido-NAD is a NAD + analog that can be used for visualization of intracellular Poly(ADP ribos)ylation (PARylation) processes .
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Target:
Cat. No.: HY-131009A
Research Areas:
Fluorescein-NAD + sodium is a fluorescent NAD + analog that can be used in studies related to the detection of ADP-ribosylation reactions. Fluorescein-NAD + sodium enables visualization of ADP-ribose groups, thereby facilitating the detection of ADP-ribosylation reactions. Fluorescein-NAD + sodium serves as a substrate for detecting the auto-ribosylation activity of SIRT6 and the ADP-ribosylation of RhoA by C3larvin toxin .
Cat. No.: HY-131485A
CAS No.: 86-08-8
Synonyms: 3-APAD, 95%; 3-Acetylpyridine NAD, 95%
Cat. No.: HY-127127A
CAS No.: 104809-38-3
Research Areas:
Deamino-NAD sodium is a structural analog of NAD+ (HY-B0445). Deamino-NAD sodium is involved in glycolysis as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH), with a Km of 2300 pm, and a Kd of 112 pm .
Cat. No.: HY-134280
CAS No.: 477782-33-5
Synonyms: Nicotinamide 8-Br-hypoxanthine dinucleotide
Target:
Research Areas:
8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog .
Cat. No.: HY-134300A
Synonyms: 8-Dimethylamino-NAD+ sodium
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8-DMA-NAD+ (sodium) (8-Dimethylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-DMA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations .
Cat. No.: HY-134305A
Synonyms: 8-Methylamino-NAD+ sodium
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8-MA-NAD+ (sodium) (8-Methylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-MA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations. 8-MA-NAD+ (sodium) can be used in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
Cat. No.: HY-131829A
Synonyms: 6-AE-NAD+ sodium
Target:
Research Areas:
N6-(2-Aminoethyl)-NAD+ (6-AE-NAD+) sodium is an adenine-modified NAD analog with coenzyme activity and the property of targeting lactate dehydrogenase (LDH). N6-(2-Aminoethyl)-NAD+ sodium undergoes transient affinity binding with LDH, thereby crosslinking the enzyme monolayer into an integrated electrode. N6-(2-Aminoethyl)-NAD + is a component of the PQQ (HY-100196)-NAD + binary interface, and supports the bioelectrocatalytic oxidation of lactate through PQQ-mediated immobilized NADH oxidation .
Cat. No.: HY-DY1108
CAS No.: 38806-38-1
Synonyms: ε-NAD (solution)
Research Areas:
Nicotinamide 1,N6-ethenoadenine dinucleotide (solution) (ε-NAD (solution)) is a fluorescent analog of NAD. Nicotinamide 1,N6-ethenoadenine dinucleotide can be cleaved by phosphodiesterase I (from C. adamanteus venom) and binds to bovine liver glutamate dehydrogenase. Nicotinamide 1,N6-ethenoadenine dinucleotide can serve as a substrate for G-ADP ribosylation of G proteins catalyzed by bacterial toxins. Nicotinamide 1,N6-ethenoadenine dinucleotide can be used as a fluorescent substrate for the study of ADP ribosylation reactions .
Solvent and concentration: ddH2O: 20 mM
Solvent and concentration: ddH2O: 20 mM
Cat. No.: HY-183044
CAS No.: 1049800-47-6
Target:
Research Areas:
SIRT1 activator 4 is an orally active, NAD +-independent SIRT1 activator. SIRT1 activator 4 is also an analog of (E)-2'-desmethyl Sulindac (HY-B0008), with weak or negligible inhibitory activity against COX-1 and no inhibitory activity against COX-2. SIRT1 activator 4 can be used for the research of metabolic diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
