1 Result for "

NF157

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NF157" in MCE Product Catalog:

Cat. No.: HY-108672
CAS No.: 104869-26-3
Purity:  92.9%
Target:  

P2Y Receptor

Research Areas:  

Inflammation/Immunology

NF157 is a highly selective nanomolar P2Y11 antagonist with a pKi of 7.35. The IC50s are 463 nM, 1811 µM, 170 µM for P2Y11 (Ki=44.3 nM), P2Y1 (Ki=187 µM), P2Y2 (Ki=28.9 µM), respectively . NF157, significantly reduces expression of metalloproteinase (MMP)-3, MMP-13, can be used in the treatment of osteoarthritis (OA) .
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