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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
NPSR
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "NPSR" in MCE Product Catalog:
1
1 Cited Publications
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SHA 68 is a potent and selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50s of 22.0 and 23.8 nM for NPSR Asn 107 and NPSR Ile 107, respectively. SHA 68 has limited the blood-brain barrier (BBB) penetration and the activity in neuralgia .
Cat. No.: HY-P1389
CAS No.: 412938-67-1
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Synonyms: NCGC84
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ML154 (NCGC84) is a selective, brain-penetrant and non-peptide neuropeptide S receptor (NPSR) antagonist with a pA2 of 9.98. ML154 potently inhibits NPS-stimulated cellular calcium, cAMP, and ERK phosphorylation responses with IC50 values of 36.5 nM, 22.1 nM, and 9.3 nM, respectively .
Cat. No.: HY-111308
CAS No.: 847554-50-1
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RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration .
Cat. No.: HY-175813
CAS No.: 3113770-74-1
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NPSR1 antagonist-1 is a potent and peripherally restricted neuropeptide S receptor 1 (NPSR1) antagonist. NPSR1 antagonist-1 can inhibit IL-6, PTGS2, IL-20, and CXCL8 expression. NPSR1 antagonist-1 can reduce TNF-α cytokine levels. NPSR1 antagonist-1 can be used for the research of inflammation, such as peritonitis .
Cat. No.: HY-RS09503
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NPSR1 Human Pre-designed siRNA Set A contains three designed siRNAs for NPSR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21667
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Npsr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npsr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-108625R
CAS No.: 847553-89-3
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SHA 68 (Standard) is the analytical standard of SHA 68. This product is intended for research and analytical applications. SHA 68 is a potent and selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50s of 22.0 and 23.8 nM for NPSR Asn107 and NPSR Ile107, respectively. SHA 68 has limited the blood-brain barrier (BBB) penetration and the activity in neuralgia .
Cat. No.: HY-P1389A
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Cat. No.: HY-180875
CAS No.: 884141-05-3
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NPSR1 modulator-1 is a NPSR1 modulator.
Cat. No.: HY-P1437A
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Cat. No.: HY-RS28185
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Npsr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Npsr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-186034
CAS No.: 2138445-51-7
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R06039-691 is a neuropeptide S receptor (NPSR) agonist with an EC50 of 93 nM. R06039-691 can participate in regulating various biological functions such as arousal, stress and anxiety responses, memory processes, and food intake by activating NPSR .
Cat. No.: HY-186036
CAS No.: 2138444-75-2
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R06039-641 is a neuropeptide S receptor (NPSR) agonist with an EC50 of 169 nM. R06039-641 can participate in regulating various biological functions such as arousal, stress and anxiety responses, memory processes, and food intake by activating NPSR .
Cat. No.: HY-186032
CAS No.: 2138295-88-0
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R06039-641 is a neuropeptide S receptor (NPSR) agonist with an EC50 of 169 nM. R06039-641 can participate in regulating various biological functions such as arousal, stress and anxiety responses, memory processes, and food intake by activating NPSR .
Cat. No.: HY-186033
CAS No.: 2138295-90-4
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R06039-696 is a neuropeptide S receptor (NPSR) agonist with an EC50 of 91 nM. R06039-696 can participate in regulating various biological functions such as arousal, stress and anxiety responses, memory processes, and food intake by activating NPSR .
Cat. No.: HY-186035
CAS No.: 2138444-70-7
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R06039-636 is an agonist of the Neuropeptide S receptor (NPSR) with an EC50 value of 94nM .
Cat. No.: HY-P1389S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
