4 Results for "

P388/ADR

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "P388/ADR" in MCE Product Catalog:

Cat. No.: HY-12458
CAS No.: 118292-36-7
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection Cancer

Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml .
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Cat. No.: HY-136514
CAS No.: 83166-17-0
Target:  

Serotonin Transporter

Research Areas:  

Cancer

Tampramine (47), a phenothiazine, could reverse multidrug resistance, with ED50 values of 60 μM (P388 cells) and 60 μM (P388/ADR cells), respectively .
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Cat. No.: HY-126735
CAS No.: 99260-71-6
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Saquayamycin D is an antibiotic, which can be isolated from Streptomyces nodosus culture broth. Saquayamycin D exhibits antibacterial activity against various gram-positive bacteria with MIC of 12.5-50 μg/mL. Saquayamycin D inhibits the proliferation of Doxorubicin (HY-15142)-sensitive P388/S and Doxorubicin-resistant P388/ADR with IC50 of 0.15 and 0.15 μg/mL .
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Cat. No.: HY-126170
CAS No.: 101961-60-8
Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A)-sensitive), and P388/ADR (doxorubicin-resistant), with IC50 of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice .
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