2 Results for "

PAM212

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PAM212" in MCE Product Catalog:

1
TB500
TB500
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1 Cited Publications
Cat. No.: HY-P0170
CAS No.: 885340-08-9
Target:  

Drug Derivative Akt P2X Receptor

Research Areas:  

Inflammation/Immunology

TB500 is a synthetic version of an active region of thymosin β4. TB500 exhibits anti-fibrotic and wound healing activities by inhibiting the Akt signaling pathway and binding to actin. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation .
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Eupalinolide A
Eupalinolide A
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Cat. No.: HY-N0754
CAS No.: 877822-40-7
Category:  

Melilotus albus Desr. Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields Inflammation/Immunology

Target:  

YAP HSP Reactive Oxygen Species (ROS) ERK Autophagy Apoptosis Tyrosinase DNA/RNA Synthesis

Eupalinolide A is a Yes-associated protein (YAP) degrader and HSP70 inducer. Eupalinolide A inhibits osteogenic differentiation of tendon-derived stem cells (TDSCs). Eupalinolide A induces autophagy in hepatocellular carcinoma cells via activating the ROS/ERK signaling pathway. Eupalinolide A protects PAM212 cells from UVB-, Menadione (HY-B0332)-, or heat shock-induced apoptosis. Eupalinolide A alleviates trauma-induced heterotopic ossification (HO) of Achilles tendon and inhibits growth of MHCC97-L and HCCLM3 hepatocellular carcinoma xenograft tumors in mice. Eupalinolide A can be used for the study of traumatic heterotopic ossification of tendons and hepatocellular carcinoma .
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