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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
90 Results for "
PD-L1 ligand
" in MedChemExpress (MCE) Product Catalog:
Products (90)
90 Results for "PD-L1 ligand" in MCE Product Catalog:
40
40 Publications Verification
Cat. No.: HY-P9904
CAS No.: 1380723-44-3
Synonyms: MPDL3280A; RG-7446; RO-5541267
Target:
Research Areas:
9
9 Cited Publications
Cat. No.: HY-P73361
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; Programmed Cell Death 1 ligand 1; Programmed Death ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:
Human
Source:
HEK293
4
Category:
Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Araliaceae Cancer
Target:
3
Target:
Research Areas:
3
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P70632
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; Programmed Cell Death 1 ligand 1; Programmed Death ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:
Mouse
Source:
HEK293
1
1
1 Cited Publications
Cat. No.: HY-P7397
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; Programmed Cell Death 1 ligand 1; Programmed Death ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:
Human
Source:
CHO
Cat. No.: HY-P9978
CAS No.: 1924598-82-2
Synonyms: JS-001
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Cat. No.: HY-P990788
Target:
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Cat. No.: HY-P99618
CAS No.: 2377419-89-9
Synonyms: IBI-315; BH2950
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Cat. No.: HY-P10439
CAS No.: 2349354-64-7
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Cat. No.: HY-P99345
CAS No.: 2022215-59-2
Synonyms: TSR-042; ANB-011; WBP-285
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Cat. No.: HY-P99114
CAS No.: 2256084-03-2
Target:
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Synonyms: T785 hydrochloride
Target:
Research Areas:
AXC-715 (T785) hydrochloride is a TLR7/TLR8 dual agonist. AXC-715 can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants .
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PROTAC PD-1/PD-L1 degrader-1, a PD-1/PD-L1 PROTAC based on Cereblon E3 ligand, inhibits PD-1/PD-L1 interaction with an IC50 of 39.2 nM. PROTAC PD-1/PD-L1 degrader-1 significantly restores the immunity repressed in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells. PROTAC PD-1/PD-L1 degrader-1 moderately reduces the protein levels of PD-L1 in a lysosome-dependent manner .
Research Areas:
BMS-37 is a PD-1/PD-L1 immune checkpoint inhibitor with an IC50 towards the PD-L1/PD-1 complex in the range of 18 to 200 nM. BMS-37 shows unspecific toxicity against modified Jurkat T cells with an EC50 between 3 and 6 µM. BMS-37 can be used for the study of the PD-L1-induced exhaustion of T-cells or as PD-L1 ligand to synthesize PROTAC molecules .
Cat. No.: HY-P3440
CAS No.: 1886057-64-2
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E3 ligase Ligand PG is a E3 ligase ligand that can be used in the recruitment of CRBN protein. E3 ligase Ligand PG exhibits potent binding activity with CRBN (IC50 of 2.191 μM). E3 ligase Ligand PG can be connected to the BMS-202 (HY-19745) by a linker to form PROTAC, PROTAC PD-L1 degrader-1 (HY-163757) .
Cat. No.: HY-P99475
CAS No.: 2460539-60-8
Synonyms: MSB-2311
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
