1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. AXC-715 hydrochloride

AXC-715 hydrochloride  (Synonyms: T785 hydrochloride)

Cat. No.: HY-138139A
Handling Instructions

AXC-715 (T785) hydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1. AXC-715, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants.

For research use only. We do not sell to patients.

AXC-715 hydrochloride Chemical Structure

AXC-715 hydrochloride Chemical Structure

CAS No. : 2490497-93-1

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Description

AXC-715 (T785) hydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].

IC50 & Target[1]

TLR8

 

TLR7

 

Molecular Weight

347.89

Formula

C18H26ClN5

CAS No.
SMILES

NCCCCN1C(CCCC)=NC2=C1C3=CC=CC=C3N=C2N.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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AXC-715 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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AXC-715 hydrochloride
Cat. No.:
HY-138139A
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