14149-34-9

E3 ligase Ligand PG Chemical Structure
14149-34-9

Chemical Structure

E3 ligase Ligand PG

  • CAS No.: 14149-34-9
  • Formula:C11H11NO2
  • Molecular Weight:189.21

IUPAC Name: 3-phenylpiperidine-2,6-dione

InChIKey: KAKZYGLQCHMNGS-UHFFFAOYSA-N

SMILES: O=C1CCC(C(N1)=O)C2=CC=CC=C2

Biological Activity: E3 ligase Ligand PG is a E3 ligase ligand that can be used in the recruitment of CRBN protein. E3 ligase Ligand PG exhibits potent binding activity with CRBN (IC50 of 2.191 μM). E3 ligase Ligand PG can be connected to the BMS-202 (HY-19745) by a linker to form PROTAC, PROTAC PD-L1 degrader-1 (HY-163757)[1].

Cat. No. Product Name Purity Description Pricing
HY-150839 		E3 ligase Ligand PG 99.94% E3 ligase Ligand PG is a E3 ligase ligand that can be used in the recruitment of CRBN protein. E3 ligase Ligand PG exhibits potent binding activity with CRBN (IC50 of 2.191 μM). E3 ligase Ligand PG can be connected to the BMS-202 (HY-19745) by a linker to form PROTAC, PROTAC PD-L1 degrader-1 (HY-163757).
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