14149-34-9

E3 ligase Ligand PG Chemical Structure
14149-34-9

Chemical Structure

E3 ligase Ligand PG

  • CAS No.: 14149-34-9
  • Formula:C11H11NO2
  • Molecular Weight:189.21

IUPAC Name: 5-methylpyrimidine-2,4(1H,3H)-dione-1,3-15N2

InChIKey: KAKZYGLQCHMNGS-UHFFFAOYSA-N

SMILES: O=C1CCC(C(N1)=O)C2=CC=CC=C2

Biological Activity: E3 ligase Ligand PG is an E3 ligase CRBN ligand with an IC50 of 2.191 μM. E3 ligase Ligand PG can be connected to BMS-202 (HY-19745) via a linker to form the PROTAC PROTAC PD-L1 degrader-1 (HY-163757)[1].

Cat. No. Product Name Purity Description Pricing
HY-150839
E3 ligase Ligand PG 99.94% E3 ligase Ligand PG is an E3 ligase CRBN ligand with an IC50 of 2.191 μM. E3 ligase Ligand PG can be connected to BMS-202 (HY-19745) via a linker to form the PROTAC PROTAC PD-L1 degrader-1 (HY-163757).
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Amount:

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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References