14149-34-9
Chemical Structure
E3 ligase Ligand PG
- CAS No.: 14149-34-9
- Formula:C11H11NO2
- Molecular Weight:189.21
IUPAC Name: 5-methylpyrimidine-2,4(1H,3H)-dione-1,3-15N2
InChIKey: KAKZYGLQCHMNGS-UHFFFAOYSA-N
SMILES: O=C1CCC(C(N1)=O)C2=CC=CC=C2
Biological Activity: E3 ligase Ligand PG is an E3 ligase CRBN ligand with an IC50 of 2.191 μM. E3 ligase Ligand PG can be connected to BMS-202 (HY-19745) via a linker to form the PROTAC PROTAC PD-L1 degrader-1 (HY-163757)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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E3 ligase Ligand PG | 99.94% | E3 ligase Ligand PG is an E3 ligase CRBN ligand with an IC50 of 2.191 μM. E3 ligase Ligand PG can be connected to BMS-202 (HY-19745) via a linker to form the PROTAC PROTAC PD-L1 degrader-1 (HY-163757). | ||||||||||||||||||||
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