157 Results for "

PEGylated conjugates

" in MedChemExpress (MCE) Product Catalog:
Products (157)

157 Results for "PEGylated conjugates" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
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Cat. No.: HY-W011556
CAS No.: 94790-35-9
Synonyms: TCFH
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) is a powerful coupling and derivatizing reagent for ester prodrug synthesis. N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate can be used for antitumor drugs before medicine research .
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Cat. No.: HY-172279A
Target:  

Liposome

Research Areas:  

Cancer

DSPE-PEG2000-TAT is a cell-penetrating peptide-modified PEGylated phospholipid conjugate and cellular uptake enhancer. DSPE-PEG2000-TAT forms via conjugation of Cys-TAT to DSPE-PEG2000-Mal. DSPE-PEG2000-TAT enhances liposomal cellular uptake and siRNA transfection efficiency in glomerular mesangial and macrophage cells. DSPE-PEG2000-TAT can be used for drug delivery .
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Cat. No.: HY-140735
Purity:  ≥95.0%
Target:  

Liposome

Research Areas:  

Others

DSPE-PEG5000-Amine (DSPE-PEG5000-ammonium) is an amino-functionalized PEGylated lipid. DSPE-PEG5000-Amine can be conjugated with chlorin e6 (Ce6) via EDC/NHS coupling. It can also be conjugated with FITC to prepare DSPE-PEG-FITC. DSPE-PEG5000-Amine is applicable to research related to PEGylated lipid functionalization and bioconjugation .
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Cat. No.: HY-155907
CAS No.: 474922-26-4
Synonyms: DSPE-PEG5000-NH2 ammonium
Target:  

Liposome

Research Areas:  

Others

DSPE-PEG5000-Amine ammonium (DSPE-PEG5000-NH2 ammonium) is an amino-functionalized PEGylated lipid. DSPE-PEG5000-Amine ammonium can be conjugated with chlorin e6 (Ce6) via EDC/NHS coupling. It can also be conjugated with FITC to prepare DSPE-PEG-FITC. DSPE-PEG5000-Amine ammonium is applicable to research related to PEGylated lipid functionalization and bioconjugation .
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Cat. No.: HY-155927
CAS No.: 474922-82-2
Synonyms: 14:0 PEG1000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
Target:  

Liposome

Research Areas:  

Others

DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a methoxy-capped PEGylated phospholipid containing two C14 lipid chains and a PEG1000 group. DMPE-PEG1000 can be incorporated as a PEG-lipid component into conjugated polymer nanoparticles for nanoparticle surface modification. DMPE-PEG1000 ammonium is applicable for researches related to PEGylated nanoparticle preparation and fluorescence imaging .
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Cat. No.: HY-136772
CAS No.: 2380273-67-4
Purity:  97.05%
Research Areas:  

Others

Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand .
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Cat. No.: HY-137895
CAS No.: 40127-11-5
Purity:  99.84%
Synonyms: H-Arg-pNA 2HCl, 98%
L-Arginine p-nitroanilide dihydrochloride, 98% (H-Arg-pNA 2HCl, 98%) is a chromogenic substrate for cathepsin H. L-Arginine p-nitroanilide dihydrochloride, 98% can be hydrolyzed to produce a chromogenic product detectable by photometry, which is used to measure the activities of cathepsin H and aminopeptidases .
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Cat. No.: HY-187333A
Synonyms: Alkyne-PEG2000-Cys-SRNLIDC
Alkyne-PEG2000-LyP-1 is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, PEG, and LyP-1 peptide (CGNKRTRGC) (HY-P2526) as the terminal targeting/functional ligand. Alkyne-PEG2000-LyP-1 is used for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-187276A
Alkyne-PEG2000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. Alkyne-PEG2000-TAT does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-184568A
Alkyne-PEG2000-iRGD is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and iRGD peptide (HY-P0122) as the terminal targeting/functional ligand. Alkyne-PEG2000-iRGD does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-184569A
Alkyne-PEG2000-WYRGRL is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and WYRGRL peptide (HY-P10739)as the terminal targeting/functional ligand. Alkyne-PEG2000-WYRGRL does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-184575A
Alkyne-PEG2000-T7 is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and T7 peptide (HAIYPRH) as the terminal targeting/functional ligand. Alkyne-PEG2000-T7 does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-187311A
Alkyne-PEG2000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. Alkyne-PEG2000-cRGD does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-187316A
Synonyms: Alkyne-PEG2000-APWHLSSQYSRT
Alkyne-PEG2000-CTP is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and CTP (cardiotropic targeting peptide) (HY-P4094) as the terminal targeting/functional ligand. Alkyne-PEG2000-CTP does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-187279A
Synonyms: Alkyne-PEG2000-CSRNLIDC
Alkyne-PEG2000-pPB (Alkyne-PEG2000-CSRNLIDC) is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, PEG, and platelet-derived growth factor receptor β-binding peptide (pPB peptide (HY-P11549)) as the terminal targeting/functional ligand. Alkyne-PEG2000-pPB does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-187324A
Alkyne-PEG2000-GE11 is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and GE11 peptide (YHWYGYTPQNVI) (HY-P10128) as the terminal targeting/functional ligand. Alkyne-PEG2000-GE11 does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-187325A
Alkyne-PEG2000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. Alkyne-PEG2000-RVG29 does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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Cat. No.: HY-185585
CAS No.: 303983-00-8
Target:  

Drug Intermediate

Research Areas:  

Cancer

JNJ-27548547, Mitomycin C (HY-13316) prodrug, is a Mitomycin C and lipophilic group conjugate. JNJ-27548547 undergoes thiolytic cleavage of its dithiobenzyl linker in the presence of reducing agents to release active substance Mitomycin C. JNJ-27548547 is formulated into pegylated liposomes (PL-MLP) with high antitumor activity in mice models .
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Cat. No.: HY-187236
Synonyms: DOPE-PEG1000-APWHLSSQYSRT
Research Areas:  

Others

DOPE-PEG1000-CTP is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and CTP (cardiotropic targeting peptide) (HY-P4094) as the terminal targeting/functional ligand. DOPE-PEG1000-CTP can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers, conferring cardiac targeting capability.
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