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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
PMM-302
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "PMM-302" in MCE Product Catalog:
Cat. No.: HY-186330
CAS No.: 2763421-81-2
Synonyms: PMMB-302
Target:
Research Areas:
PMM-302 (PMMB-302) is a shikonin N-benzyl sophoridate derivative and a telomerase inhibitor. PMM-302 downregulates the telomerase core proteins DKC1 and NHP2 as well as TERT mRNA, and inhibits telomerase activity. PMM-302 induces G2/M phase cell cycle arrest and apoptosis, accompanied by downregulation of Bcl2, Bcl-XL, and FADD and upregulation of cleaved caspase-3 and cleaved caspase-9. PMM-302 can be used for lung cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
