87 Results for "

Peptide F

" in MedChemExpress (MCE) Product Catalog:
Products (87)

87 Results for "Peptide F" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-P1119
CAS No.: 878557-55-2
Research Areas:  

Neurological Disease

WRW4, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide .
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9
9 Cited Publications
Cat. No.: HY-P0027
CAS No.: 102396-24-7
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .
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2
2 Cited Publications
Cat. No.: HY-P2929B
CAS No.: 83534-39-8
Target:  

Glycosidase

Research Areas:  

Others

PNGase F (Immobilized, Microspin) is a resin in which PNGase F (peptide N-glycosidase F) is covalently coupled to agarose beads, and it is used to remove N-glycans from antibodies, fusion proteins and other N-glycosylated proteins. The enzyme is recombinantly expressed in Escherichia coli, with its sequence derived from Flavobacterium meningsepticum .
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1
1 Cited Publications
Cat. No.: HY-P77083
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MEP1A; Meprin A, Alpha (PABA Peptide Hydrolase); Meprin A Subunit Alpha; PPH Alpha; PABA Peptide Hydrolase; BA268F1.1 (Meprin A Alpha (PABA Peptide Hydrolase)); Endopeptidase-2; Metalloendopeptidase; PPHA; Meprin A Subunit; N-Benzoyl-L-Tyrosyl-P-Amino-Ben
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-B0383
CAS No.: 181183-52-8
Synonyms: PNU180638
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Almotriptan malate (PNU180638) is an orally active, highly selective agonist of the 5-HT1B/1D receptor (5-HT1B/1D receptor), with EC50 values of 1.6 nM and 3.1 nM, respectively. Almotriptan malate shows moderate affinity for the 5-HT1F receptor, and weak affinity for the 5-HT1A, 5-HT6 and 5-HT7 receptors. Almotriptan malate induces intracranial vasoconstriction, inhibits nociceptive neurotransmission in the trigeminocervical complex, and suppresses the release of vasoactive peptides from trigeminal nerve endings. Almotriptan malate can be used in research related to migraine .
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Cat. No.: HY-162275
CAS No.: 861224-48-8
Research Areas:  

Cancer

JMJD1C-IN-1 is an orally active and selective inhibitor of JMJD1C (IC50 = 0.59 μM, Kd = 1.96 μM). JMJD1C-IN-1 inhibits the binding of JMJD1C to H3K9me2 peptide substrate in the HTRF assay (IC50 = 1.47 μM). JMJD1C-IN-1 disrupts intratumoral regulatory T (Treg) cell fitness by dual mechanisms: promoting H3K9me2 accumulation to downregulate PD1 expression and reducing STAT3 demethylation to enhance STAT3 activation. JMJD1C-IN-1 demonstrates dose-dependent antitumor efficacy in multiple mouse tumor models (MCA205 fibrosarcoma, B16-F10 melanoma, LLC lung cancer, Hepa1-6 hepatocellular carcinoma, CT26 colorectal cancer). JMJD1C-IN-1 can be used for the study of tumor immunotherapy by selectively targeting intratumoral Treg cells .
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Cat. No.: HY-P99879
CAS No.: 2200269-79-8
Synonyms: Benegrastim; Bineuta; F 627

Target:  

STAT

Research Areas:  

Inflammation/Immunology

Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .
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Cat. No.: HY-B0383A
CAS No.: 154323-57-6
Synonyms: PNU180638 free base
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Almotriptan (PNU180638 free base) is an orally active, highly selective agonist of the 5-HT1B/1D receptor (5-HT1B/1D receptor), with EC50 values of 1.6 nM and 3.1 nM, respectively. Almotriptan shows moderate affinity for the 5-HT1F receptor, and weak affinity for the 5-HT1A, 5-HT6 and 5-HT7 receptors. Almotriptan induces intracranial vasoconstriction, inhibits nociceptive neurotransmission in the trigeminocervical complex, and suppresses the release of vasoactive peptides from trigeminal nerve endings. Almotriptan can be used in research related to migraine .
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Cat. No.: HY-P6365B
CAS No.: 452782-06-8
Synonyms: D-4F
Target:  

Apolipoprotein

Research Areas:  

Cardiovascular Disease

APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases .
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Cat. No.: HY-P4072A
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

(D)-PPA 1 TFA is a hydrolysisresistant d-peptide antagonist. (D)-PPA 1 TFA serves as a potent PD-1/PD-L1 inhibitor. (D)-PPA 1 TFA binds to PD-1 with the affinity 0f 0.51 μM with in vitro and in vivo efficacy .
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Cat. No.: HY-P10792
CAS No.: 1644155-35-0
Target:  

EGFR

Research Areas:  

Cancer

HER2-targeted peptide H6F is a HER2 targeting peptide that binds to HER2 to target breast cancer cells, with the amino acid sequence YLFFVFER. The HER2-targeted peptide H6F can be conjugated with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Single-photon emission computed tomography (SPECT) imaging shows that the labeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MBA-453 tumor-bearing mice models. The HER2-targeted peptide H6F can be used for tumor molecular imaging studies .
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Cat. No.: HY-P4933
CAS No.: 2022995-68-0
Synonyms: Tau-F protein (255-314)
Target:  

Tau Protein

Research Areas:  

Neurological Disease

Tau Peptide (255-314) (Repeat 2 Domain) (human) (Tau-F protein (255-314)) is a polypeptide. Tau Peptide (255-314) (human) is the 255-314 fragment of Tau-F (also known as Tau-4, the 2N4 isoform), a major isoform of the Tau protein. Tau Peptide (255-314) (human) contains two core driving sequences for Tau aggregation, namely PHF6* (275-280, VQIINK) and PHF6 (306-311, VQIVYK), and spans the C-terminal half of repeat domain R1, the entire repeat domain R2, and the N-terminal half of repeat domain R3 within the microtubule-binding region (MTBR).
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Cat. No.: HY-132988
CAS No.: 2254698-84-3
Research Areas:  

Others

Fmoc-Tyr(3-F,tBu)-OH is an Fmoc-labeled amino acid derivative. Fmoc-Tyr(3-F,tBu)-OH can be used for peptide synthesis .
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Cat. No.: HY-P10310A
Target:  

HIV

Research Areas:  

Infection

F9170 TFA is an amphipathic peptide with an activity of inactivate HIV-1 virions. F9170 TFA targets the conserved cytoplasmic tail of HIV-1 env and disrupts the integrity of the viral membrane. F9170 TFA is able to cross the blood-brain barrier (BBB) .
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Cat. No.: HY-P6365
Synonyms: L-4F TFA
Target:  

Apolipoprotein

Research Areas:  

Cardiovascular Disease

APL180 TFA (L-4F) is an apolipoprotein AI mimetic peptide that enhances the anti-inflammatory activity of high-density lipoprotein (HDL). APL180 can be used in the study of cardiovascular diseases.
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Cat. No.: HY-W1048555A
Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells .
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Cat. No.: HY-W123015
CAS No.: 79598-53-1
Target:  

Drug Intermediate

Research Areas:  

Others

6-Azidohexanoic acid is an azide-containing carboxylic acid. 6-Azidohexanoic acid can serve as an azide-containing fragment to conjugate with peptides, enabling click chemistry-based radiolabeling with [ 18F]FNPB. 6-Azidohexanoic acid acts as a starting material for the synthesis of biotin azide .
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Cat. No.: HY-172699
Target:  

Liposome LDLR

Research Areas:  

Cancer

DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties .
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Cat. No.: HY-P11312
CAS No.: 2770688-17-8
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

[S5K, F6Y, L9mL, M10Mox] neurokinin A (4-10) is a neuropeptide A analog and a peptide fragment of EB1002 (HY-P10746). [S5K, F6Y, L9mL, M10Mox] neurokinin A (4-10) is highly selective for mouse tachykinin receptors and human tachykinin receptor NK1R .
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Cat. No.: HY-164576
CAS No.: 1374994-81-6
Synonyms: NODA-Bz-SCN
Research Areas:  

Cancer

NCS-MP-NODA (NODA-Bz-SCN) is a NODA-derived bifunctional chelator. NCS-MP-NODA can conjugate with biomolecules including the RGD tripeptide, and is used for aluminum-[ 18F] fluoride-based positron emission tomography (PET) radiolabeling. NCS-MP-NODA can conjugate with the free lysine amino group of the PD-L1-specific peptide DK221 to generate DK222, which can be radiolabeled with 18F to form [ 18F]DK222. NCS-MP-NODA can be used in studies related to triple-negative breast cancer, melanoma and colon cancer .
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