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Phloroglucinol

" in MedChemExpress (MCE) Product Catalog:

標的別:	Amylases (1) Antibiotic (1) Apoptosis (5) Bacterial (3) Bcl-2 Family (1) Biochemical Assay Reagents (3) Caspase (1) COX (1) Endogenous Metabolite (3) Fungal (1) GABA Receptor (1) Glycosidase (1) Influenza Virus (1) Isotope-Labeled Compounds (2) Reactive Oxygen Species (ROS) (2) Reference Standards (3)
研究分野別:	Cancer (4) Cardiovascular Disease (3) Infection (5) Metabolic Disease (4) Neurological Disease (1)

阻害剤およびアゴニスト

生化学アッセイ試薬

天然物

同位体標識化合物

製品番号	製品名	Target	研究分野	構造式

HY-101193

Zinc Protoporphyrin Maximum Cited Publications 67 Publications Verification Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9	Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor. Zinc Protoporphyrin regulates expression of HO-1 at the transcriptional level. The effect of Zinc Protoporphyrin on HO-1 expression is controversial. It was shown to induce HO-1 expression in some cells, but suppress it in others. Zinc Protoporphyrin is used as a screening marker of iron deficiency in vivo. Zinc Protoporphyrin has anti-cancer activity .

HY-Y0678

1,3,5-Trimethoxybenzene 1 Publications Verification TRIMETHYL Phloroglucinol	Biochemical Assay Reagents	Others
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl ⁺) and free bromine (Br ⁺). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .

HY-N6084

Humulone α-Lupulic acid	COX GABA Receptor Apoptosis	Cardiovascular Disease
Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABA_A receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis-inducing properties .

HY-N11729

*Pyrogallol-phloroglucinol-6,6-bieckol*	Others	Others
Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia .

HY-N3340

Macrocarpal I	Fungal	Infection
Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC₅₀ value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .

HY-W001117

3,5-Dimethoxyphenol Phloroglucinol Dimethyl Ether	Endogenous Metabolite	Metabolic Disease
3,5-Dimethoxyphenol is a toxin metabolite, found in human consuming yew leaves .

HY-N3343

Macrocarpal D (-)-Macrocarpal D	Bacterial	Infection
Macrocarpal D is a potent antibacterial agent. Macrocarpal D is a phloroglucinol dialdehyde diterpene derivatives that can be found in the leaves of Eucalyptus macrocarpa .

HY-101193R

Zinc Protoporphyrin (Standard) Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc Protoporphyrin-9 (Standard)	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-N7179

7-Hydroxy-5-methoxycoumarin	Others	Others
7-Hydroxy-5-methoxycoumarin is a phloroglucinol-type furocoumarins, a potent naturally-occurring insect antifeedant .

HY-N3342

Macrocarpal E	Bacterial	Infection
Macrocarpal E is a potent antibacterial agent. Macrocarpal E is a phloroglucinol dialdehyde diterpene derivatives that can be found in the leaves of Eucalyptus macrocarpa .

HY-W017195

Isopropyl benzoate Propan-2-yl benzoate	Biochemical Assay Reagents	Others
Isopropyl benzoate is a class of esters consisting of a benzene ring and an isopropyl group attached to a carboxylic acid group. Isopropyl benzoate can be used as an inducer to biosynthesize phloroglucinol in E. coli .

HY-108164

Aspidin BB	Apoptosis Bcl-2 Family Caspase	Cancer
Aspidin BB is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii. Aspidin BB has anticancer activity. Aspidin BB induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells .

HY-N0530

Dryocrassin ABBA 2 Publications Verification Dryocrassin	Apoptosis Influenza Virus	Cancer
Dryocrassin ABBA (Dryocrassin) is an orally active phloroglucinol derivative that can be extracted from Phyllopteris officinalis. Dryocrassin ABBA has antitumor and antiviral activity. Dryocrassin ABBA induced apoptosis of human hepatocellular carcinoma cells through mitochondrial pathway mediated by Caspase .

HY-N11728

*2,7"-Phloroglucinol-6,6'-bieckol*	Amylases Glycosidase	Metabolic Disease
2,7"-Phloroglucinol-6,6'-bieckol is an orally active dual α-amylase/α-glucosidase inhibitor with IC₅₀ values of 6.94 μM and 23.35 μM respectively. 2,7"-Phloroglucinol-6, 6'-bieckol alleviates postprandial hyperglycemia in diabetic mice. 2,7"-Phloroglucinol-6,6'-bieckol can be used in diabetes research .

HY-N3079

Phlorin Phloroglucinol β-D-glucoside	Others	Others
Phlorin (Phloroglucinol β-D-glucoside) is a phloroglucinol (PG) glucoside .

HY-Y0678R

1,3,5-Trimethoxybenzene (Standard)	Reference Standards Biochemical Assay Reagents	Others
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl+) and free bromine (Br+). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .

HY-123350

Saroaspidin B	Antibiotic	Infection
Saroaspidin B, a dimer of a phloroglucinol moiety, is an antibiotic compound .

HY-Y0678S

1,3,5-Trimethoxybenzene-d3 Trimethyl Phloroglucinol-d₃	Isotope-Labeled Compounds	Neurological Disease
1,3,5-Trimethoxybenzene-d3 (Trimethyl phloroglucinol-d3) is the deuterium labeled 1,3,5-Trimethoxybenzene (HY-Y0678). 1,3,5-Trimethoxybenzene is a key component of the Chinese rose odor. 1,3,5-Trimethoxybenzene is synthesized in three successive methylation steps from phloroglucinol, the initial precursor .

HY-144571S

*Trimethyl phloroglucinol-d9*	Isotope-Labeled Compounds	Others
Trimethyl phloroglucinol-d₉ is the deuterium labeled Trimethyl phloroglucinol.

HY-146196

Anticandidal agent-1	Bacterial	Infection
Anticandidal agent-1 (compound c2) is a potent and broad-spectrum anticandidal agent. Anticandidal agent-1 shows anticandidal activity against C. albicans and C. glabrata, with MIC₅₀ values of 8.65 and 13.51 μg/mL, respectively. Anticandidal agent-1 inhibits biofilm by blocking hyphal elongation and filamentation .

HY-N9272

2-Methyl-4-(2-methylbutyryl)phloroglucinol	Others	Others
2-Methyl-4-(2-methylbutyryl)phloroglucinol is a Phenols product that can be isolated from the herbs of Eucalyptus robusta .

HY-N8044

Ebracteolatain A	Others	Others
Ebracteolatain A is a phloroglucinol derivative found in the roots of Euphorbia ebracteolata Hayata .

HY-N11959

Perforatumone	Others	Others
Perforatumone is a phloroglucinol derivative that can be found in the aerial parts of Hypericum perforatum .

HY-N9309

2,6-Dimethyl-3-O-methyl-4-(2-methylbutyryl)phloroglucinol	Others	Others
2,6-Dimethyl-3-O-methyl-4-(2-methylbutyryl)phloroglucinol is a Phenols product that can be isolated from the herbs of Eucalyptus robusta .

HY-W015406R

Benzene-1,3,5-triol dihydrate (Standard) Phloroglucinol dihydrate (Standard)	Reference Standards
Benzene-1,3,5-triol dihydrate (Standard) is the analytical standard of Benzene-1,3,5-triol dihydrate. This product is intended for research and analytical applications.

Isopropyl benzoate Propan-2-yl benzoate	生化学アッセイ試薬
Isopropyl benzoate is a class of esters consisting of a benzene ring and an isopropyl group attached to a carboxylic acid group. Isopropyl benzoate can be used as an inducer to biosynthesize phloroglucinol in E. coli .

製品番号	製品名	Category	Target	構造式

HY-101193

Zinc Protoporphyrin Maximum Cited Publications 67 Publications Verification Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9	Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification Cancer	Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor. Zinc Protoporphyrin regulates expression of HO-1 at the transcriptional level. The effect of Zinc Protoporphyrin on HO-1 expression is controversial. It was shown to induce HO-1 expression in some cells, but suppress it in others. Zinc Protoporphyrin is used as a screening marker of iron deficiency in vivo. Zinc Protoporphyrin has anti-cancer activity .

HY-Y0678

1,3,5-Trimethoxybenzene 1 Publications Verification TRIMETHYL Phloroglucinol	Structural Classification 天然物 Rosaceae Plants Rosa rugosa Thunb. Source Classification	Biochemical Assay Reagents
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl ⁺) and free bromine (Br ⁺). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .

HY-N6084

Humulone α-Lupulic acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Humulus lupulus L. Plants Moraceae Disease Research Fields Source Classification	COX GABA Receptor Apoptosis
Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABA_A receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis-inducing properties .

HY-N11729

*Pyrogallol-phloroglucinol-6,6-bieckol*	Microorganisms Phenols Polyphenols Source Classification	Others
Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia .

HY-N3340

Macrocarpal I	Terpenoids Sesquiterpenes Phenols Polyphenols Myrtaceae Plants Eucalyptus globulus Labill. Source Classification	Fungal
Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC₅₀ value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .

HY-W001117

3,5-Dimethoxyphenol Phloroglucinol Dimethyl Ether	Schisandra sphenanthera Rehd. et Wils Monophenols Classification of Application Fields Taxaceae Phenols Metabolic Disease Plants Schisandraceae Disease Research Fields Source Classification Taxus chinensis (Pilger) Rehd.	Endogenous Metabolite
3,5-Dimethoxyphenol is a toxin metabolite, found in human consuming yew leaves .

HY-N3343

Macrocarpal D (-)-Macrocarpal D	Eucalyptus macrocarpa Hook. Terpenoids Sesquiterpenes Phenols Polyphenols Myrtaceae Plants	Bacterial
Macrocarpal D is a potent antibacterial agent. Macrocarpal D is a phloroglucinol dialdehyde diterpene derivatives that can be found in the leaves of Eucalyptus macrocarpa .

HY-101193R

Zinc Protoporphyrin (Standard) Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc Protoporphyrin-9 (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis
Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-N7179

7-Hydroxy-5-methoxycoumarin	Coumarins Phenylpropanoids Plants Convolvulaceae Ipomoea batatas (Linn.) Lamarck Source Classification	Others
7-Hydroxy-5-methoxycoumarin is a phloroglucinol-type furocoumarins, a potent naturally-occurring insect antifeedant .

HY-N3342

Macrocarpal E	Eucalyptus macrocarpa Hook. Terpenoids Sesquiterpenes Myrtaceae Plants	Bacterial
Macrocarpal E is a potent antibacterial agent. Macrocarpal E is a phloroglucinol dialdehyde diterpene derivatives that can be found in the leaves of Eucalyptus macrocarpa .

HY-108164

Aspidin BB	Dryopteridaceae Dryopteris championii (Benth.) C. Chr. Plants Source Classification	Apoptosis Bcl-2 Family Caspase
Aspidin BB is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii. Aspidin BB has anticancer activity. Aspidin BB induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells .

HY-N0530

Dryocrassin ABBA 2 Publications Verification Dryocrassin	Infection Classification of Application Fields Dryopteridaceae Phenols Polyphenols Dryopteris crassirhizoma Nakai Plants Disease Research Fields Source Classification	Apoptosis Influenza Virus
Dryocrassin ABBA (Dryocrassin) is an orally active phloroglucinol derivative that can be extracted from Phyllopteris officinalis. Dryocrassin ABBA has antitumor and antiviral activity. Dryocrassin ABBA induced apoptosis of human hepatocellular carcinoma cells through mitochondrial pathway mediated by Caspase .

HY-N11728

*2,7"-Phloroglucinol-6,6'-bieckol*	Microorganisms Phenols Polyphenols Source Classification	Amylases Glycosidase
2,7"-Phloroglucinol-6,6'-bieckol is an orally active dual α-amylase/α-glucosidase inhibitor with IC₅₀ values of 6.94 μM and 23.35 μM respectively. 2,7"-Phloroglucinol-6, 6'-bieckol alleviates postprandial hyperglycemia in diabetic mice. 2,7"-Phloroglucinol-6,6'-bieckol can be used in diabetes research .

HY-N3079

Phlorin Phloroglucinol β-D-glucoside	Urginea Steinh. Phenols Polyphenols Plants Saccharides Monosaccharides Source Classification Asparagaceae Juss.	Others
Phlorin (Phloroglucinol β-D-glucoside) is a phloroglucinol (PG) glucoside .

HY-Y0678R

1,3,5-Trimethoxybenzene (Standard)	Structural Classification 天然物 Rosaceae Plants Rosa rugosa Thunb. Source Classification	Reference Standards Biochemical Assay Reagents
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl+) and free bromine (Br+). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .

HY-123350

Saroaspidin B	Antibiotics Guttiferae Plants Hypericum japonicum Thunb. ex Murray Other Antibiotics Source Classification	Antibiotic
Saroaspidin B, a dimer of a phloroglucinol moiety, is an antibiotic compound .

HY-N9272

2-Methyl-4-(2-methylbutyryl)phloroglucinol	Eucalyptus robusta Sm. Phenols Polyphenols Myrtaceae Plants Source Classification	Others
2-Methyl-4-(2-methylbutyryl)phloroglucinol is a Phenols product that can be isolated from the herbs of Eucalyptus robusta .

HY-N8044

Ebracteolatain A	Structural Classification 天然物 Euphorbiaceae Plants Euphorbia kansuensis Prokh. Source Classification	Others
Ebracteolatain A is a phloroglucinol derivative found in the roots of Euphorbia ebracteolata Hayata .

HY-N11959

Perforatumone	Structural Classification 天然物 Guttiferae Hyperlcurn perforatum L. Plants Source Classification	Others
Perforatumone is a phloroglucinol derivative that can be found in the aerial parts of Hypericum perforatum .

HY-N9309

2,6-Dimethyl-3-O-methyl-4-(2-methylbutyryl)phloroglucinol	Phenols Myrtaceae Plants Eucalyptus robusta Smith Source Classification	Others
2,6-Dimethyl-3-O-methyl-4-(2-methylbutyryl)phloroglucinol is a Phenols product that can be isolated from the herbs of Eucalyptus robusta .

製品番号	製品名	構造式

HY-Y0678S

1,3,5-Trimethoxybenzene-d3
1,3,5-Trimethoxybenzene-d3 (Trimethyl phloroglucinol-d3) is the deuterium labeled 1,3,5-Trimethoxybenzene (HY-Y0678). 1,3,5-Trimethoxybenzene is a key component of the Chinese rose odor. 1,3,5-Trimethoxybenzene is synthesized in three successive methylation steps from phloroglucinol, the initial precursor .

HY-144571S

*Trimethyl phloroglucinol-d9*
Trimethyl phloroglucinol-d₉ is the deuterium labeled Trimethyl phloroglucinol.

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