1 Result for "

PolQi2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PolQi2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-150279
CAS No.: 2565638-16-4
Purity:  99.65%
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

PolQi2 is a PolΘ inhibitor that targets and inhibits alt-EJ (alternative end-joining) repair by inhibiting the helicase domain at the N-terminus of PolΘ. PolQi2 enhances the precision and integration efficiency of gene editing at different loci and in various cell lines. Furthermore, the combined use of PolQi2 with DNA-PK inhibitors reduces the off-target effects of Cas9. PolQi2 can be used in gene editing research [2].
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