Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
Proteasome-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "Proteasome-IN-1" in MCE Product Catalog:
Cat. No.: HY-100172
CAS No.: 374080-21-4
Target:
Research Areas:
Proteasome-IN-1 is a proteasome inhibitor extracted from patent WO 2013142376 A1.
12
12 Publications Verification
Cat. No.: HY-P9915
CAS No.: 945721-28-8
Synonyms: Anti-Human CD38, Human Antibody; HuMax-CD38; JNJ-54767414
Target:
Research Areas:
12
12 Publications Verification
Cat. No.: HY-P9915A
CAS No.: 945721-28-8
Synonyms: Anti-Human CD38, Human Antibody (PBS)
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-N2166
CAS No.: 17406-45-0
Synonyms: α-TomatINe; LycopersicIN; TomatIN
Category:
Target:
2
2 Cited Publications
Cat. No.: HY-19726
CAS No.: 803647-40-7
NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway . NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling .
1
Target:
Research Areas:
Target:
Research Areas:
20S Proteasome activator 1 is a potent 20S proteasome activator with EC200 values of 0.3 μM, 0.7 μM and 1.8 μM for trypsin-like site, chymotrypsin-like site and caspase-like site. 20S Proteasome activator 1 translates well in a cellular system, preventing the accumulation of the pathogenic A53T mutant of α-synuclein. 20S Proteasome activator 1 can be used for researching neurodegenerative diseases [1].
Target:
Research Areas:
Enzyme-IN-1 (compound 1) is a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases. Specifically, Enzyme-IN-1 inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. Enzyme-IN-1 may has potential antiinflammatory properties [1].
Target:
Research Areas:
20S Proteasome-IN-1 is a 26S proteasome inhibitor extracted from patent WO2006128196A2 compound 2. 20S Proteasome-IN-1 has the potential for cancer, immune-related disorders, inflammation, ischemic conditions, neurodegenerative disorders and other diseases research [1].
Cat. No.: HY-P1258
CAS No.: 158442-41-2
Synonyms: Proteasome INhibitor 1; Z-Ile-Glu(OtBu)-Ala-Leu-CHO
Target:
Cat. No.: HY-N2166R
CAS No.: 17406-45-0
Synonyms: α-TomatINe (Standard); LycopersicIN (Standard); TomatIN (Standard)
Category:
Target:
Cat. No.: HY-179273
CAS No.: 3097658-48-2
Target:
Research Areas:
Proteasome-IN-1 (Compound 130) is a proteasome inhibitor. Proteasome-IN-1 exhibits antiparasitic activity against P. faciparum 3D7 [1].
Cat. No.: HY-144983
CAS No.: 2377849-57-3
Target:
Research Areas:
E3 ligase Ligand 22 (compound 139) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway .
Cat. No.: HY-157212
Target:
Research Areas:
PARP-1/Proteasome-IN-1 (compound 42i) is a dual PARP-1 and proteasome inhibitor with significant inhibitory effects on breast cancer. PARP-1/Proteasome-IN-1 can downregulate the expression of BRCA1 and RAD51 to inhibit homologous recombination repair function and induce apoptosis [1].
Cat. No.: HY-157032
CAS No.: 1613134-34-1
Target:
Research Areas:
Proteasome-IN-5 (compound 5) is a proteasome inhibitor .
Cat. No.: HY-P10003A
Target:
Research Areas:
Cat. No.: HY-N11620
Category:
Target:
Cat. No.: HY-N11621
Category:
Target:
Cat. No.: HY-144980
CAS No.: 2504233-73-0
Target:
Research Areas:
E3 ligase Ligand 21 (compound 2) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway .
Target:
Research Areas:
E3 ligase Ligand 23 (compound 17-6) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
