Enzyme-IN-1
Based on 1 Customer Validation
Enzyme-IN-1 (compound 1) is a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases. Specifically, Enzyme-IN-1 inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. Enzyme-IN-1 may has potential antiinflammatory properties.
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- Reinheit : 95.19%
- CAS. Nr.: 868540-02-7
- Formel: C36H50N4O7
- Molecular Weight:650.80
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 868540-02-7
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Appearance Solid
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Molecular Weight 650.80
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Formel C36H50N4O7
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Color White to off-white
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SMILES
OCC(N[C@@H](CCC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C([C@]3(CO3)C)=O)=O)=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 50 mg/mL (76.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5366 mL | 7.6829 mL | 15.3657 mL | 38.4143 mL |
| 5 mM | 0.3073 mL | 1.5366 mL | 3.0731 mL | 7.6829 mL | |
| 10 mM | 0.1537 mL | 0.7683 mL | 1.5366 mL | 3.8414 mL | |
| 15 mM | 0.1024 mL | 0.5122 mL | 1.0244 mL | 2.5610 mL | |
| 20 mM | 0.0768 mL | 0.3841 mL | 0.7683 mL | 1.9207 mL | |
| 25 mM | 0.0615 mL | 0.3073 mL | 0.6146 mL | 1.5366 mL | |
| 30 mM | 0.0512 mL | 0.2561 mL | 0.5122 mL | 1.2805 mL | |
| 40 mM | 0.0384 mL | 0.1921 mL | 0.3841 mL | 0.9604 mL | |
| 50 mM | 0.0307 mL | 0.1537 mL | 0.3073 mL | 0.7683 mL | |
| 60 mM | 0.0256 mL | 0.1280 mL | 0.2561 mL | 0.6402 mL |