Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
ROCE
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "ROCE" in MCE Product Catalog:
9
9 Publications Verification
Cat. No.: HY-W017018
CAS No.: 3184-13-2
3
3 Cited Publications
Cat. No.: HY-19408
CAS No.: 1315323-00-2
Target:
Research Areas:
Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca 2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 μM (IC50 of 13.08 μM for store operated Ca 2+ entry in BRL-2H3 cells). Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels .
1
1 Cited Publications
Synonyms: N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide
Target:
Research Areas:
Pyr6 is a selective store operated calcium entry (SOCE) inhibitor with an IC50 of 0.49 μM. Pyr6 displays 37-fold higher potency for RBL SOCE than for TRPC3 ROCE .
Cat. No.: HY-W017018S2
CAS No.: 943962-21-8
Cat. No.: HY-W017018B
CAS No.: 3184-13-2
Cat. No.: HY-W017018S
CAS No.: 347841-40-1
Cat. No.: HY-W017018S4
CAS No.: 2483831-57-6
Cat. No.: HY-W017018S5
CAS No.: 360565-59-9
Cat. No.: HY-W017018R
CAS No.: 3184-13-2
Category:
Cat. No.: HY-W017018S3
CAS No.: 2483831-42-9
Cat. No.: HY-W017018S1
CAS No.: 224054-19-7
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
