25 Results for "

S-methyltransferase

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "S-methyltransferase" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-134124
CAS. Nr.: 92614-59-0
Reinheit:  95.8%
Forschungsgebiete:  

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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1
1 Cited Publications
Art. -Nr.: HY-A0248A
CAS. Nr.: 4135-11-9
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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1
1 Cited Publications
Art. -Nr.: HY-P1108
CAS. Nr.: 681260-70-8
Target:  

CRFR

Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
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1
1 Cited Publications
Art. -Nr.: HY-P1108A
Target:  

CRFR

Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
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Art. -Nr.: HY-P10272
CAS. Nr.: 1628323-80-7
Synonyms: PTG-300
Target:  

Ferroportin

Forschungsgebiete:  

Others

Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
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Art. -Nr.: HY-126426
CAS. Nr.: 88096-02-0
Target:  

DNA Methyltransferase

Forschungsgebiete:  

Cardiovascular Disease

CBHcy is an inhibitor for betaine-homocysteine S-methyltransferase (BGMT), with an IC50 of 0.09 μM. CBHcy upregulates the plasma total homocysteine and causes transient hyperhomocysteinemia in mice model .
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Art. -Nr.: HY-N6655
CAS. Nr.: 3493-12-7
Synonyms: DL-MMSC
DL-Methionine methylsulfonium chloride (DL-MMSC) is an orally effective methionine-derived sulfonium salt that promotes gastric emptying and gastrointestinal transit. DL-Methionine methylsulfonium chloride attenuates oxidative stress and inflammatory responses, and enhances anti-apoptotic (apoptosis) signaling, thereby ameliorating Sodium metabisulfite (HY-Y1326)-induced testicular dysfunction and semen quality impairment. DL-Methionine methylsulfonium chloride is applicable for research on functional dyspepsia, gastrointestinal motility, and male reproductive function injury .
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Art. -Nr.: HY-P10143
CAS. Nr.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Target:  

MMP

Forschungsgebiete:  

Others

MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .
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Art. -Nr.: HY-A0248AS
Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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Art. -Nr.: HY-P10563
CAS. Nr.: 2580150-96-3
Synonyms: BHV-1100
Target:  

CD38 IFNAR

Forschungsgebiete:  

Cancer

Noraramtide (BHV-1100) is an antibody-recruiting molecule. Noraramtide binds to CD38 and recruits natural killer (NK) cells to mediate antibody-dependent cellular cytotoxicity. Noraramtide enhances the capacity of autologous cytokine-induced memory-like (CIML) NK cells to produce IFNγ and CD107a, thereby improving their cytotoxicity against multiple myeloma cells. Noraramtide can be used in the research of multiple myeloma .
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Art. -Nr.: HY-P3066
CAS. Nr.: 77453-01-1
Synonyms: d(CH2)5Tyr(Et)VAVP
Target:  

Vasopressin Receptor

Forschungsgebiete:  

Metabolic Disease

SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
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Art. -Nr.: HY-E71932
Forschungsgebiete:  

Others

5-Methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (EC 2.1.1.14) is a transferase that can convert 5-methyltetrahydropteroyltri-L-glutamate and L-homocysteine into tetrahydropteroyltri-L-glutamate and L-methionine.
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Art. -Nr.: HY-E70349
CAS. Nr.: 9029-78-1
Target:  

Endogenous Metabolite

Forschungsgebiete:  

Others

Betaine homocysteine S-methyltransferase is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
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Art. -Nr.: HY-P10828
CAS. Nr.: 1260620-30-1
Target:  

Virus Protease

Forschungsgebiete:  

Infection Inflammation/Immunology

MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
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Art. -Nr.: HY-P82804
Synonyms: BHMT; Betaine--homocysteine S-methyltransferase 1

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Art. -Nr.: HY-P85053
Synonyms: BHMT; Betaine--homocysteine S-methyltransferase 1

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P4756
CAS. Nr.: 282725-67-1
Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Others

N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Art. -Nr.: HY-P705431
Reinheit:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TMT1B; Thiol S-methyltransferase METTL7B; Prev. METTL7B; Thiol S-methyltransferase TMT1B; ALDI; methyltransferase Like 7B; methyltransferase-Like Protein 7B; MGC17301; Thiol methyltransferase 1B; Associated With Lipid Droplets 1
Species:  
Human
Source:  
E. coli
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Art. -Nr.: HY-P2592
CAS. Nr.: 113714-78-6
Forschungsgebiete:  

Others

Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .
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Art. -Nr.: HY-125628
CAS. Nr.: 179733-11-0
Target:  

Endogenous Metabolite

Forschungsgebiete:  

Infection

Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .
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