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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10128 Results for "
SET
" in MedChemExpress (MCE) Product Catalog:
Products (10128)
10128 Results for "SET" in MCE Product Catalog:
14
14 Publications Verification
Cat. No.: HY-18627A
CAS No.: 1627607-87-7
Synonyms: (R)-PFI-2 hydrochloride
Target:
Research Areas:
PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis .
14
Target:
Research Areas:
PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride, a chemical probe, is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis .
6
6 Cited Publications
Cat. No.: HY-141539A
Purity: 99.77%
Target:
Research Areas:
SETDB1-TTD-IN-1 TFA is a potent, selective and endogenous binder competitive ligand of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD) that binds to TTD, with a Kd of 88 nM. SETDB1-TTD-IN-1 TFA increases SETDB1 methyltransferase activity. SETDB1-TTD-IN-1 TFA can be used for the research of biological functions and disease associations of SETDB1-TTD .
2
2 Cited Publications
Target:
Research Areas:
SET2 is a selective TRPV2 antagonist (IC50=0.46 μM). SET2 blocks the TRP channel and suppresses prostate cancer cells migration. SET2 reduces the lysophosphatidic acid (LPA, a TRPV2 activator)-induced cytoplasmic calcium increases .
2
2 Cited Publications
Target:
Research Areas:
MR837 is an inhibitor of NSD2-PWWP1. MR837 can bind with human nuclear receptor binding SET domain protein 2 (PWWP domain) .
2
2 Cited Publications
Cat. No.: HY-P74394
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VTCN1; V-SET Domain Containing T Cell Activation Inhibitor 1; B7-H4; B7H4; B7h.5; B7S1; B7x; V-SET Domain-Containing T-Cell Activation Inhibitor 1; Immune Costimulatory Protein B7-H4; B7 Superfamily Member 1; B7 Family Member, H4; B7 Homolog 4; FLJ22418; T Cell Costimulatory Molecule B7x; T-Cell Costimulatory Molecule B7x; Protein B7S1; PRO1291; VCTN1
Species:
Mouse
Source:
HEK293
1
Target:
Research Areas:
Gintemetostat (KTX-1001) is an orally active, highly specific NSD2/MMSET histone methyltransferase inhibitor with human NSD2 IC50 values ranging 0.460-2.17 nM and NSD2 SET domain IC50 of 2.32 nM and Kd values ranging 6.3-70.4 nM .Gintemetostat reduces H3K36me2 levels, impairs multiple myeloma cell adhesion and colony formation, enhances cytotoxicity, boosts T-cell activation, and sensitizes resistant multiple myeloma cells to other agents .Gintemetostat can be used for the research of multiple myeloma and relapsed and refractory multiple myeloma .
1
1 Cited Publications
Target:
Research Areas:
Ipflufenoquin is an insecticide with the potential to control primary infection with apple scab. Ipflufenoquin should be applied between half an inch of green and fruit set .
1
1 Cited Publications
Cat. No.: HY-RS14075
Target:
Research Areas:
SYK Human Pre-designed siRNA Set A contains three designed siRNAs for SYK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
1
1 Cited Publications
Cat. No.: HY-P74613
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KMT5A; Lysine N-Methyltransferase 5A; Prev. SETD8; H4-K20-HMTase KMT5A; PR-SET7; PR/SET07; SET07; [Histone H4]-Lysine(20) N-Methyltransferase; SET8; H4-K20-Specific Histone Methyltransferase; SET Domain Containing (Lysine Methyltransferase) 8; Histone-Lys
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P76079
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SMYD2; Histone Methyltransferase SMYD2; SET And MYND Domain Containing 2; ZMYND14; HSKM-B; Lysine N-Methyltransferase 3C; KMT3C; [Histone H3]-Lysine(4) N-Trimethyltransferase; SET And MYND Domain-Containing Protein 2; Zinc Finger, MYND Domain Containing 1
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P72428
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIR; V-SET Immunoregulatory Receptor; C10orf54; SISP1; VISTA; B7-H5; PD-1H; Dies1; GI24; B7H5; V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation; V-SET Domain-Containing Immunoregulatory Receptor; V-Domain Ig Suppressor Of T Cell Ac
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74395
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VTCN1; V-SET Domain Containing T Cell Activation Inhibitor 1; B7-H4; B7H4; B7h.5; B7S1; B7x; V-SET Domain-Containing T-Cell Activation Inhibitor 1; Immune Costimulatory Protein B7-H4; B7 Superfamily Member 1; B7 Family Member, H4; B7 Homolog 4; FLJ22418;
Species:
Human
Source:
HEK293
NSD2-IN-1 (compound 38) is a potent and high selective NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1) inhibitor, with an IC50 of 0.11 μM. NSD2-IN-1 can bind to NSD2-PWWP1 and then affect the expression of genes regulated by NSD2. NSD2-IN-1 induces apoptosis and cell cycle arrest .
Cat. No.: HY-177605
Target:
Research Areas:
ddNTP Set trisodium contains ddATP (HY-128036B), ddCTP (HY-137697D), ddGTP (HY-134103A), and ddTTP (HY-137694B).
Cat. No.: HY-RS00166
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Research Areas:
ACLY Human Pre-designed siRNA Set A contains three designed siRNAs for ACLY gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29482
Target:
Research Areas:
CERS6 Cattle Pre-designed siRNA Set A is a siRNA containing three designed siRNAs for CERS6 gene (Cattle).
Cat. No.: HY-RS00035
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Research Areas:
AATK Human Pre-designed siRNA Set A contains three designed siRNAs for AATK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00122
Target:
Research Areas:
ACACB Human Pre-designed siRNA Set A contains three designed siRNAs for ACACB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00130
Target:
Research Areas:
ACADSB Human Pre-designed siRNA Set A contains three designed siRNAs for ACADSB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
