1 Result for "

SHAPE-JuMP experiments

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SHAPE-JuMP experiments" in MCE Product Catalog:

Cat. No.: HY-76222
CAS No.: 118-48-9
Target:  

Drug Intermediate

Research Areas:  

Others

Isatoic anhydride is a single-adduct forming reagent and a monofunctional SHAPE reagent. Isatoic anhydride reacts with the 2'-hydroxyl group of RNA nucleotides via a single reactive group to form a single adduct, without forming cross-links between nucleotides. In SHAPE-JuMP experiments, Isatoic anhydride serves as a control reagent for single-adduct formation, which is used to distinguish true cross-links from single-adduct formation .
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