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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
Schistosomiasis
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "Schistosomiasis" in MCE Product Catalog:
3
Category:
Infection Microorganisms Ginkgoaceae Terpenoids Ginkgo biloba L. Diterpenoids Plants Disease Research Fields Food Research
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2
2 Cited Publications
Cat. No.: HY-B0244
CAS No.: 55268-74-1
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Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis .
2
Hycanthone is an apurinic/apyrimidinic endonuclease 1 (APE1) inhibitor, DNA intercalator and Antischistosomal agent, with an IC50 of 80 nM against APE1. Hycanthone irreversibly inhibits thymidine incorporation into DNA in adult sensitive *Schistosoma mansoni*, while exerts weak inhibitory effects on uridine and leucine incorporation. Hycanthone reduces influenza virus-induced interferon production. Hycanthone exhibits mutagenic effects in various organisms, shows teratogenicity in mice and rabbits, and induces neoplastic liver lesions in partially hepatectomized mice. Hycanthone can be used in research related to schistosomiasis and cancer .
1
1 Cited Publications
Cat. No.: HY-10416
CAS No.: 21738-42-1
Oxamniquine is a potent agent for the treatment of schistosomiasis.
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1,2-Dimyristoyl-sn-glycerol is a protein kinase C activator.1,2-Dimyristoyl-sn-glycerol activates PKC α.1,2-Dimyristoyl-sn-glycerol induces increased acetylcholinesterase (AChE) activity in Schistosoma mansoni.1,2-Dimyristoyl-sn-glycerol can be used for the research of schistosomiasis .
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DAUDA is a fluorescent fatty acid analog probe, with Kd values of 0.63 μM, 0.82 μM, and 0.66 μM against subtypes/mutants of Schistosoma mansoni Sm14 fatty acid-binding protein, respectively. DAUDA binds to Sm14 fatty acid-binding protein variants, enters their non-polar binding pockets and alters fluorescence emission properties. DAUDA serves as a tracer in competitive binding assays with natural fatty acids to evaluate the fatty acid-binding capacity of Sm14 protein variants. DAUDA is applicable to the research of schistosomiasis .
Cat. No.: HY-N10534
CAS No.: 71208-06-5
Synonyms: Lewis X
Category:
Infection Polysaccharides Animals Disease Research Fields Inflammation/Immunology Saccharides Cancer
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Cat. No.: HY-N4184
CAS No.: 91433-17-9
Cat. No.: HY-Y1890C
CAS No.: 61791-12-6
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(R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer .
Cat. No.: HY-175184
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LSD1-IN-44 (Compound 19) is a LSD1 inhibitor with an IC50 of 0.02 μM for LSD1-CoREST enzymatic complex. LSD1-IN-44 has significant antischistosomal activity against transformed schistosomula (NTS) and Schistosoma mansoni adult worms while showing a delayed onset of action towards juvenile forms. LSD1-IN-44 has no significant toxicity to human cells. LSD1-IN-44 can be used for schistosomiasis research .
Cat. No.: HY-101725A
CAS No.: 86630-81-1
Synonyms: Ro 11-3624; Ro 11-3624/001
(R)-Meclonazepam (Ro 11-3624) is an inactive enantiomer of Meclonazepam. Meclonazepam is a benzodiazepine derivative with anti-schistosomiasis activities .
Cat. No.: HY-161596
SmCB1-IN-1 (Compound 2h) is an inhibitor for S. mansoni cathepsin B1 (SmCB1) with an Ki of 0.05 μM . SmCB1-IN-1 exhibits selectivity toward human off-target cathepsins (29% and 37% inhibition for CatB and CatL at 20 μM). SmCB1-IN-1 inhibits 68% Schistosoma mansoni at 1 μM .
Cat. No.: HY-B0244R
CAS No.: 55268-74-1
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Praziquantel (Standard) is the analytical standard of Praziquantel. This product is intended for research and analytical applications. Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis .
Cat. No.: HY-151433
CAS No.: 2138480-87-0
Antiparasitic agent-10 (Compound 94) is an anti-parasitic agent, shows anti-schistosomal activity. Antiparasitic agent-10 shows activity against adults of Schistosoma mansoni, and can be used in Schistosomiasis research .
Cat. No.: HY-168547S
CAS No.: 3021566-15-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
