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Results for "

Sheep erythrocytes

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Akt (1) Apoptosis (1) Bacterial (3) Bcl-2 Family (1) Biochemical Assay Reagents (1) Caspase (1) Cholinesterase (ChE) (1) Complement System (1) COX (1) DNA/RNA Synthesis (2) Environmental Pollutants (1) Fungal (1) Interleukin Related (3) Lipoxygenase (1) Mitochondrial Metabolism (1) MMP (1) mTOR (1) Phosphatase (3) Phospholipase (1) PI3K (1) Reactive Oxygen Species (ROS) (2) Reference Standards (1) TNF Receptor (2)
By Research Areas:	Cancer (2) Infection (3) Inflammation/Immunology (6) Metabolic Disease (2) Neurological Disease (1)

By Targets:

Acyltransferase (1)

Akt (1)

Apoptosis (1)

Bacterial (3)

Bcl-2 Family (1)

Biochemical Assay Reagents (1)

Caspase (1)

Cholinesterase (ChE) (1)

Complement System (1)

COX (1)

DNA/RNA Synthesis (2)

Environmental Pollutants (1)

Fungal (1)

Interleukin Related (3)

Lipoxygenase (1)

Mitochondrial Metabolism (1)

MMP (1)

mTOR (1)

Phosphatase (3)

Phospholipase (1)

PI3K (1)

Reactive Oxygen Species (ROS) (2)

Reference Standards (1)

TNF Receptor (2)

By Research Areas:

Cancer (2)

Infection (3)

Inflammation/Immunology (6)

Metabolic Disease (2)

Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0850

Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed) 3 Publications Verification	Environmental Pollutants Biochemical Assay Reagents	Neurological Disease
Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed) is a non-biodegradable, hydrophilic, odorless biomedical polymer with cell adhesion/proliferation inhibition, peripheral nerve regeneration induction, dissolution enhancement, and non-toxic, biocompatible properties .

HY-P2460

SMAP-29	Bacterial Fungal Interleukin Related TNF Receptor	Infection Inflammation/Immunology
SMAP‑29 is a cathelicidin antimicrobial peptide with LPS‑binding and anti‑inflammatory properties. SMAP‑29 exerts broad‑spectrum antimicrobial activity against bacteria, fungi and multidrug‑resistant isolates. SMAP‑29 kills pathogens by permeabilizing bacterial membranes, inducing depolarization and cell lysis, and also inhibits inflammatory cytokines while reducing lethality in septic shock and pneumonia models. SMAP-29 can be used for research on bacterial infections, drug-resistant infections, septic shock .

HY-N3087

Phaseollin 1 Publications Verification	Others	Others
Phaseollin is an isoflavonoid phytoalexin that can be isolated from Phaseolus vulgaris . Phaseollin is toxic to bean hypocotyl and endocarp cells, and causes a complete lysis of sheep erythrocytes .

HY-W016433

2-Aminofluorene	DNA/RNA Synthesis	Others
2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis .

HY-W016433R

2-Aminofluorene (Standard)	Reference Standards DNA/RNA Synthesis	Others
2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis .

HY-P990268

Anti-Mouse CD45.2 Antibody (104.2)	Phosphatase	Inflammation/Immunology
Anti-Mouse CD45.2 Antibody (104.2) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse CD45.2. Anti-Mouse CD45.2 Antibody (104.2) can inhibit B Cell differentiation. Anti-Mouse CD45.2 Antibody (104.2) can be used for the researches of inflammation and immunology, such as LPS (HY-D1056)-induced inflammation and autoimmunity .

HY-W371164

C1s-IN-1	Complement System	Inflammation/Immunology
C1s-IN-1 (compound A1) is a selective and competitive inhibitor of C1s. C1s-IN-1 binds directly to C1s with a K_d of 9.8 μM .

HY-170650

SMase-IN-1	Phospholipase Cholinesterase (ChE) Bacterial	Infection Inflammation/Immunology
SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase enzyme (SMase) inhibitor (IC₅₀ value for B. cereus SMase is 6.43 µM). SMase-IN-1 also inhibits eqBuChE (59.50% inhibition rate at 50 µM concentration). SMase-IN-1 forms a complex with Cu ²⁺ in biometal interactions. SMase-IN-1 reduces B. cereus-induced hemolysis on sheep erythrocytes .

HY-168960

ROS inducer 8	Reactive Oxygen Species (ROS) Bacterial	Infection
ROS inducer 8 (Compound 11g) is the inhibitor for glutathione (GSH), that induces the ROS accumulation in Enterococcus faecalis, thereby exhibiting antibacterial activity. ROS inducer 8 disrupts the biofilm, inhibits S. aureus and E. faecalis with MIC of 8 μg/mL and 2 μg/mL, exhibits post-antibiotic effect. ROS inducer 8 exhibits low hemolytic toxicity to sheep erythrocytes (HC₅₀ > 1280 μg/mL) .

HY-N10625A

Cyprinol 5α-Cyprinol	Phosphatase	Metabolic Disease
Cyprinol (5α-Cyprinol) is an orally active bile salt and xenochemical pheromone . Cyprinol impairs renal function and increases plasma ALP activity in rats, induces diel vertical migration in Daphnia spp., enhances the permeability of the rectal mucosa to water-soluble compounds, and aids lipid digestion in fish. Cyprinol can be used in studies of fish toxicity and acute renal failure .

HY-183764

COX-2/5-LOX-IN-8	COX Lipoxygenase TNF Receptor Interleukin Related MMP	Inflammation/Immunology
COX-2/5-LOX-IN-8 is an orally active dual COX-2/5-LOX inhibitor, with an IC₅₀ of 6.30 μM against sheep-derived COX-2 and an IC₅₀ of 8.09 μM against 5-LOX. COX-2/5-LOX-IN-8 acts as a membrane stabilizer that stabilizes erythrocyte membranes against hypotonicity-induced hemolysis. COX-2/5-LOX-IN-8 functions as a protein stabilizer that inhibits heat-induced denaturation of bovine serum albumin. COX-2/5-LOX-IN-8 reduces paw swelling, improves hind limb weight-bearing function, decreases serum levels of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6, CRP), and lowers serum levels of cartilage degradation biomarkers (COMP, MMP-3, CTX-II). COX-2/5-LOX-IN-8 can be used in the research of osteoarthritis .

HY-N17326

Ilekudinol B	Acyltransferase Phosphatase Interleukin Related	Metabolic Disease Inflammation/Immunology
Ilekudinol B is an inhibitor of ACAT and PTP1B, with an IC₅₀ of 5.3 μM and a K_i of 11.6 μM against human PTP1B. Ilekudinol B inhibits the classical pathway of the complement system, with an IC₅₀ of 51 μM. Ilekudinol B inhibits TNF-α-induced cellular IL-8 secretion, promotes glucose uptake in skeletal muscle myotubes, and acts as an insulin mimetic and insulin sensitizer. Ilekudinol B can be used in research related to type 2 diabetes, obesity, and inflammatory diseases .

HY-183327

PI3K/mTOR-IN-22	PI3K mTOR Akt Apoptosis Reactive Oxygen Species (ROS) Mitochondrial Metabolism Bcl-2 Family Caspase	Cancer
PI3K/mTOR-IN-22 is an orally active PI3K/mTOR kinase dual inhibitor with IC₅₀ values of 400.5 nM and 8.2 nM. PI3K/mTOR-IN-22 downregulates phosphorylation of the AKT and mTOR, upregulates pro-apoptotic proteins Bax and caspase-3 and downregulates anti-apoptotic protein Bcl-2. PI3K/mTOR-IN-22 exhibits antiproliferative activity against cancer cells, induces apoptosis and ROS production, and reduces mitochondrial membrane potential. PI3K/mTOR-IN-22 exhibits antitumor activity in breast cancer mice models .

Cat. No.	Product Name	Type