2-Aminofluorene
Based on 1 Customer Validation
2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 153-78-6
- Formula: C13H11N
- Molecular Weight:181.24
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
2-Aminofluorene (0-100 μM, 1-5 days) produces a dose-related suppression of the antibody response to sheep erythrocytes (SRBC), DNP-Ficoll, and LPS[2].
2-Aminofluorene (0-100 μM, 3 days, spleen cells) produces suppression on lymphoproliferative responses to LPS and Con A[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
2-Aminofluorene (60 mg/kg, i.p.) forms significantly higher levels of DNA adducts in tumor-target organs than in non-target organs in acetylator congenic hamsters[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 153-78-6
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Appearance Solid
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Molecular Weight 181.24
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Formula C13H11N
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Color Off-white to light yellow
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SMILES
NC1=CC(CC2=C3C=CC=C2)=C3C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (551.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (622 KB)
- English - EN (622 KB)
- Français - FR (622 KB)
- Deutsch - DE (622 KB)
- Norwegian - NO (622 KB)
- Español - ES (622 KB)
- Swedish - SV (622 KB)
- Italian - IT (622 KB)
- Korean - KR (622 KB)
- Portuguese - PT (622 KB)
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Handling Instructions (2659 KB)
References
[1]. Heflich RH, et al. Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites. Mutat Res. 1994 Oct;318(2):73-114. [Content Brief]
[2]. Kim BS, et al. Immunosuppressive effects of 2-acetylaminofluorene and 2-aminofluorene on murine splenocytes culture. Drug Chem Toxicol. 1989 Sep-Dec;12(3-4):297-311. [Content Brief]
[3]. Levy GN, et al. 2-Aminofluorene-DNA adduct formation in acetylator congenic mouse lines. Carcinogenesis. 1989 Apr;10(4):705-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.5175 mL | 27.5877 mL | 55.1755 mL | 137.9386 mL |
| 5 mM | 1.1035 mL | 5.5175 mL | 11.0351 mL | 27.5877 mL | |
| 10 mM | 0.5518 mL | 2.7588 mL | 5.5175 mL | 13.7939 mL | |
| 15 mM | 0.3678 mL | 1.8392 mL | 3.6784 mL | 9.1959 mL | |
| 20 mM | 0.2759 mL | 1.3794 mL | 2.7588 mL | 6.8969 mL | |
| 25 mM | 0.2207 mL | 1.1035 mL | 2.2070 mL | 5.5175 mL | |
| 30 mM | 0.1839 mL | 0.9196 mL | 1.8392 mL | 4.5980 mL | |
| 40 mM | 0.1379 mL | 0.6897 mL | 1.3794 mL | 3.4485 mL | |
| 50 mM | 0.1104 mL | 0.5518 mL | 1.1035 mL | 2.7588 mL | |
| 60 mM | 0.0920 mL | 0.4598 mL | 0.9196 mL | 2.2990 mL | |
| 80 mM | 0.0690 mL | 0.3448 mL | 0.6897 mL | 1.7242 mL | |
| 100 mM | 0.0552 mL | 0.2759 mL | 0.5518 mL | 1.3794 mL |
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