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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
Sia
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "Sia" in MCE Product Catalog:
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alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI) is a member of alpha2,8-sialyltransferase (ST8Sia) family, is often used in biochemical studies. alpha-2,8-Sialyltransferase (CstII) catalyzes elongation of the α2,8-linked oligo/polysialic acid chain on the Sia residue transferred .
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CMP-sialic acid synthetase (NmCSS) is an essential enzyme involved in the biosynthesis of carbohydrates and glycoconjugates containing sialic acids. CMP-sialic acid synthetase (NmCSS) activates free Sia, converting it to CMP-Sia, which is the only donor substrate for all sialyltransferases .
Cat. No.: HY-W011541
CAS No.: 39028-27-8
Synonyms: Iodoacetic acid N-hydroxysuccinimide ester; N-Succinimidyl Iodoacetate
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SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-159147
CAS No.: 2570251-69-1
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SIAIS039 is an orally active c-ros oncogene 1 (ROS1)-specific PROTAC with DC50s of 154.46 nM, 126.47 nM, 143.69 nM for HCC78 cells, Ba/F3 expressing the CD74-ROS1 fusion and Ba/F3 expressing the SDC4-ROS1 fusion, respectively. SIAIS039 suppresses cell proliferation, induces cell cycle arrest and apoptosis, and inhibits clonogenicity against ROS1-positive cells. SIAIS039 demonstrates anti-tumour effects against ROS1-driven tumor growth vivo. SIAIS039 is composed of the ALK inhibitor Brigatinib (HY-12857), a linker EM-12 (HY-138793), and a VHL ligand E3 ubiquitin ligase 1-Butyne (Red: Brigatinib; Blue: VHL ligand; Black: linker) .
Cat. No.: HY-RS13859
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ST8SIA5 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16251
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ST8SIA3 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P2699
CAS No.: 152617-90-8
Synonyms: GrTx; ω-GsTx Sia
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Cat. No.: HY-RS13856
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ST8SIA1 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13857
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ST8SIA2 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13858
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ST8SIA4 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13860
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ST8SIA6 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16451
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St8sia3 Rat Pre-designed siRNA Set A contains three designed siRNAs for St8sia3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28565
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St8sia1 Rat Pre-designed siRNA Set A contains three designed siRNAs for St8sia1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E70302
Synonyms: ST8Sia6
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ST8 alpha-2,8-Sialyltransferase 6 (ST8SIA6) is a sialyltransferase that generates α2,8-linked disialic acids, which bind to mouse Siglec-E and human Siglec-7 and -9, and accelerates tumor growth by suppressing anti-tumor immune responses .
Cat. No.: HY-E70300
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ST8 alpha-2,8-Sialyltransferase 8B (ST8SIA8 II) is a sialyltransferase that catalyzes the synthesis of α2,8-polysialic acid (polySia) glycans .
Cat. No.: HY-RS16366
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St8sia3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for St8sia3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22047
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St8sia1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for St8sia1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184482
CAS No.: 1019642-47-7
Synonyms: BPC-Sia-LacNAc-N3
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CD22L-N3 (BPC-Sia-LacNAc-N3) is a pharmaceutical intermediate that can be used to synthesize CD22-specific trisaccharide ligands. CD22L-N3 is applicable to the research of B-cell lymphoma .
Cat. No.: HY-E70301
Synonyms: ST8Sia4
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ST8 alpha-2,8-Sialyltransferase 4 (ST8SIA4) is a sialyltransferase that participates in the sialylation mechanism. ST8 alpha-2,8-Sialyltransferase 4 has also been implicated in breast cancer development and mediates cell proliferation and invasion of cancer cells in a sialyltransferase-dependent manner .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
