1 Result for "

TKB-LH interface

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TKB-LH interface" in MCE Product Catalog:

Cat. No.: HY-183293
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Others

Cbl-b-IN-32 is a Cbl-b inhibitor with an IC50 of 6.83 μM. Cbl-b-IN-32 binds to the TKB-LH interface, stabilizes the inactive conformation of Cbl-b, engages Tyr363 via hydrogen bonds and water bridges, and forms hydrogen bonds with Phe261 and Phe263 .
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