3 Results for "

TSLP receptor complex

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "TSLP receptor complex" in MCE Product Catalog:

Cat. No.: HY-P992378

Target:  

CCR STAT

연구분야:  

Inflammation/Immunology Cancer

HZ-1127 is a thymic stromal lymphopoietin (TSLP) inhibitor. HZ-1127 selectively binds to TSLP, blocks receptor complex interaction, inhibits STAT5 activation, downstream inflammatory signaling, and TSLP-induced CCL17 and CCL22 secretion. HZ-1127 can be used for the research of allergic diseases and cancer .
loading...
    loading...
Cat. No.: HY-P992452

Target:  

Inhibitory Antibodies

연구분야:  

Inflammation/Immunology

RO-5469754 is a humanized monoclonal antibody that specifically binds to human thymic stromal lymphopoietin (TSLP). RO-5469754 blocks the binding of hTSLP to its receptor complex, thereby neutralizing TSLP-mediated biological activities, and does not cross-react with TSLP from cynomolgus monkeys or mice. RO-5469754 can be further used to generate the bispecific antibody TAVO101 × IL4R-dupi .
loading...
    loading...
Cat. No.: HY-206870
CAS No.: 3104965-33-2
연구분야:  

Inflammation/Immunology

BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP-mediated ternary complex formation, blocks TSLPR-IL7Rα co-localization, binds and stabilizes TSLPR, and inhibits phosphorylated STAT3/6. BP79 suppresses immune cell infiltration, secretion of IL-13, IL-4. BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis .
loading...
    loading...