7 Results for "

TSU68

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "TSU68" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-10517
CAS No.: 252916-29-3
Purity:  99.13%
Synonyms: SU6668; TSU-68
Target:  

PDGFR FGFR VEGFR Apoptosis

Research Areas:  

Cancer

Orantinib (SU6668; TSU-68) is a multi-targeted receptor tyrosine kinase inhibitor with Kis of 2.1 μM, 8 nM and 1.2 μM for Flt-1, PDGFRβ and FGFR1, respectively.
loading...
    loading...
Cat. No.: HY-N11677
CAS No.: 1035154-52-9
7-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517). It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68 .
loading...
    loading...
Cat. No.: HY-N11675
CAS No.: 1035154-46-1
5-Hydroxy-TSU-68 (compound M1) is the 5-hydroxylated indolinone derivative of TSU-68. TSU-68 is an anticancer agent that inhibits angiogenic receptor tyrosine kinases .
loading...
    loading...
Cat. No.: HY-10517A
CAS No.: 210644-62-5
Purity:  99.44%
Synonyms: (Z)-SU6668; (Z)-TSU-68
Target:  

VEGFR PDGFR FGFR

Research Areas:  

Cancer

(Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk‐1/KDR, PDGFRβ, and FGFR1, with IC50s of 2.1, 0.008, and 1.2 µM, respectively. (Z)-Orantinib is a potent antiangiogenic and antitumor agent that induces regression of established tumors .
loading...
    loading...
Cat. No.: HY-N11676
CAS No.: 1035154-49-4
6-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517). It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68 .
loading...
    loading...
Cat. No.: HY-10517R
CAS No.: 252916-29-3
Synonyms: SU6668 (Standard); TSU-68 (Standard)
Research Areas:  

Cancer

Orantinib (Standard) is the analytical standard of Orantinib (HY-10517). This product is intended for research and analytical applications. Orantinib (SU6668; TSU-68) is a multi-targeted receptor tyrosine kinase inhibitor with Kis of 2.1 μM, 8 nM and 1.2 μM for Flt-1, PDGFRβ and FGFR1, respectively.
loading...
    loading...
Cat. No.: HY-10517AR
CAS No.: 210644-62-5
Synonyms: (Z)-SU6668 (Standard); (Z)-TSU-68 (Standard)
Research Areas:  

Cancer

(Z)-Orantinib (Standard) is the analytical standard of (Z)-Orantinib (HY-10517A). This product is intended for research and analytical applications. (Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk‐1/KDR, PDGFRβ, and FGFR1, with IC50s of 2.1, 0.008, and 1.2 μM, respectively. (Z)-Orantinib is a potent antiangiogenic and antitumor agent that induces regression of established tumors .
loading...
    loading...