1 Result for "

anti-tumor,cell cycle

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "anti-tumor,cell cycle" in MCE Product Catalog:

Cat. No.: HY-161324
Research Areas:  

Cancer

Tubulin degrader 1, a derivative of BML284 (HY-19987), is an orally active Tubulin degrader with anti-tumor cell proliferation activity. Tubulin degrader 1 binds to the colchicine-binding site of β-tubulin, inhibits tubulin polymerization and promotes tubulin degradation. Tubulin degrader 1 inhibits microtubule polymerization, induces G2/M cell cycle arrest and apoptosis. Tubulin degrader 1 suppresses tumor growth in ovarian cancer xenograft models, induces anti-proliferative activity against tumor cells and overcomes multidrug resistance. Tubulin degrader 1 can be used in research related to various cancers including ovarian cancer .
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