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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
bradykinin B2 receptor agonist
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "bradykinin B2 receptor agonist" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P0298A
CAS No.: 23827-91-0
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Synonyms: RMP 7
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Cat. No.: HY-P3751
CAS No.: 32222-00-7
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Cat. No.: HY-P0298
CAS No.: 15958-92-6
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Cat. No.: HY-123376
CAS No.: 193344-25-1
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FR-190997 is a non-peptide Bradykinin B2 receptor selective agonist, Ki value is 9.8 nM. FR-190997 is also an effective antihypertensive agent .
Cat. No.: HY-103295
CAS No.: 71800-36-7
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Cat. No.: HY-P3061
CAS No.: 37642-65-2
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Cat. No.: HY-103292
CAS No.: 118122-39-7
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Cat. No.: HY-118945
CAS No.: 194928-55-7
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
FR191413 is a selective bradykinin B2 receptor agonist that stimulates prostaglandin E2 production in WI-38 cells and activates BK B2 receptor-mediated pathways such as vasodilation and organ protection. FR191413 competitively binds to [ 3H]-BK in guinea pig ileum (GPI) membranes and CHO cells transfected with the human BK B2 receptor, with IC50 values of 20.0 nM and 2.60 nM, respectively. FR191413 can be used in research related to cardiovascular diseases and diabetes, including hypertension, myocardial hypertrophy, myocardial infarction, arrhythmias, and diabetic nephropathy .
Cat. No.: HY-P1650
CAS No.: 215713-39-6
Synonyms: B 9870
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Breceptin (B 9870) is an antagonist of the bradykinin B1/B2 receptor (B1/B2R). Breceptin exhibits an irreversible antagonist effect on B2R, inhibiting the vasodilation induced by Bradykinin (HY-P0206) in the rabbit carotid vein contraction experiment. B-9870 shows partial agonist properties in HEK 293 cells with high expression of B2R, and can activate ERK1/2 phosphorylation, calcium ion mobilization, arachidonic acid release, and receptor internalization. Breceptin can be used in research to inhibit breast cancer and non-small cell lung cancer .
Cat. No.: HY-103294
CAS No.: 229030-05-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
