2 Results for "

carmaphycin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "carmaphycin" in MCE Product Catalog:

Cat. No.: HY-121805
CAS No.: 1425485-72-8
Pureté:  97.52%
Target:  

ADC Linkers

Domaines de recherche:  

Cancer

DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues . DBCO- C6- acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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Cat. No.: HY-171956
CAS No.: 2143080-91-3
Target:  

Proteasome Parasite

Domaines de recherche:  

Infection

Carmaphycin-17 (CP-17) is a selective 20S proteasome inhibitor with an EC50 of 217 ?nM. Carmaphycin-17 has potent antimicrobial activity against Trichomonas vaginalis. Carmaphycin-17 overcomes Metronidazole (HY-B0318) resistance and significantly reduces parasite burden upon topical treatment without any apparent adverse effects in vaginal trichomonad infection mice model. Carmaphycin-17 can be used for sexually transmitted disease like trichomoniasis research .
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