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carrier proteins

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1119
    Triclosan
    Maximum Cited Publications
    9 Publications Verification

    		 Environmental Pollutants Antibiotic Apoptosis Bacterial Fungal Infection Cancer
    Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
    Triclosan
  • HY-B2247A
    PLGA (75:25)
    5+ Cited Publications

    poly(lactic-co-glycolic acid) (75:25)

    		 Biochemical Assay Reagents Others
    PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
    PLGA (75:25)
  • HY-125857C
    Cytochrome C (bovine heart)

    		Biochemical Assay Reagents Apoptosis Reactive Oxygen Species (ROS) Caspase Metabolic Disease
    Cytochrome C (bovine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (bovine heart) acts as an effective ROS scavenger, but when combined with the cofactor p66Shc, it promotes the generation of ROS to initiate apoptosis. Cytochrome C (bovine heart) can act as a single electron carrier .
    Cytochrome C (bovine heart)
  • HY-NP133A
    NP-KLH,Type II

    4-Hydroxy-3-nitrophenylacetyl-Keyhole Limpet Hemocyanin,Type II

    		 Biochemical Assay Reagents Inflammation/Immunology
    NP-KLH,Type II is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Keyhole Limpet Hemocyanin (KLH, a carrier protein). NP-KLH,Type II can induce specific humoral immune responses and NP-specific antibodies production. NP-KLH,Type II can act as a specific antigen tool used for immunological experiments .
    NP-KLH,Type II
  • HY-CP001
    D-Trehalose, Carrier Protein
    1 Publications Verification

    		 Biochemical Assay Reagents Metabolic Disease
    D-Trehalose is a disaccharide formed by a 1,1-glycosidic bond between two α-glucose units and is widely used as a food ingredient and pharmaceutical excipient. D-Trehalose is known to protect and stabilise proteins. For long-term storage, recombinant protein solution should be diluted further with 5% D-Trehalose, Carrier Protein.
    D-Trehalose, Carrier Protein
  • HY-NP138
    NP-OVAL (Ovalbumin)

    		Biochemical Assay Reagents Inflammation/Immunology Cancer
    NP-OVAL (Ovalbumin) is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Ovalbumin (OVAL, a carrier protein). NP-OVAL (Ovalbumin) can induce specific immune responses and NP-specific antibodies production. NP-OVAL (Ovalbumin) can accelerate the construction of multiple myeloma models .
    NP-OVAL (Ovalbumin)
  • HY-CP002
    Bovine Serum Albumin, Carrier Protein

    		Biochemical Assay Reagents Others
    Bovine Serum Albumin (BSA) is a 583 amino acid protein consisting of three homologous full alpha structural domains. BSA is a spherical protein essential for the transport of molecules such as fatty acids, drugs and hormones from the blood. It is used in many biochemical applications as a drug carrier for biologically active compounds. For long-term storage, recombinant protein solution should be diluted further with 0.1% BSA .
    Bovine Serum Albumin, Carrier Protein
  • HY-125857A
    Cytochrome C (equine heart)

    		Biochemical Assay Reagents Apoptosis Caspase Metabolic Disease
    Cytochrome C (equine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (equine heart) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (equine heart) can act as a single electron carrier .
    Cytochrome C (equine heart)
  • HY-143202
    DPhPC

    		Liposome Biochemical Assay Reagents Others
    DPhPC is a phospholipid compound characterized by high mechanical and chemical stability, broad temperature phase stability, and high electrical resistance. DPhPC readily forms unilamellar vesicles and solid-supported bilayers. DPhPC is commonly used as a component of nanoliposomal drug carriers or as a model membrane material for studies on membrane proteins/ion channels .
    DPhPC
  • HY-NP137
    NP-PE (Phycoerythrin)

    		Biochemical Assay Reagents Inflammation/Immunology
    NP-PE (Phycoerythrin) is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Phycoerythrin (PE, a carrier protein). NP-PE (Phycoerythrin) can induce the formation of specific immune complexes and mediate the targeted encounter and activation of B cells with antigens. NP-PE (Phycoerythrin) can be used to study the mechanisms by which B cells capture and transport immune complexes in lymph nodes .
    NP-PE (Phycoerythrin)
  • HY-150097
    Recombinant Human Serum Albumin(rHSA)

    		Biochemical Assay Reagents Metabolic Disease Inflammation/Immunology Cancer
    Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .
    Recombinant Human Serum Albumin(rHSA)
  • HY-156214
    NICE-01

    AP1867-PEG2-JQ1; AP-PEG2-JQ1

    		 Epigenetic Reader Domain Others
    NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound that bind to proteins in separate cellular compartments that can induce nuclear import of cytosolic cargoes, using nuclear-localized bromodomain-containing protein 4 (BRD4) as a “carrier” for co-import and nuclear trapping of cytosolic proteins .
    NICE-01
  • HY-P10502
    L57

    		LDLR Infection
    L57 is a low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 exhibits high affinity for LRP1, with an EC50 of 45 nM. L57 possesses blood-brain barrier (BBB) permeability and plasma stability. L57 can serve as a carrier for central nervous system drug delivery .
    L57
  • HY-131146
    AMOZ
    1 Publications Verification

    3-Amino-5-morpholinomethyl-2-oxazolidone

    		 Drug Metabolite Infection
    AMOZ is a carcinogenic metabolite of Furaltadone (HY-B1148A), which forms stable tissue residues by covalently binding to proteins as a hapten. AMOZ can be coupled with carrier proteins (such as BSA/OVA) to induce immune response and is released after acid hydrolysis. AMOZ residues can be detected by competitive ELISA method, and the detection limit in the monoclonal antibody 2E5.1 test is as low as 0.16 μg/kg (shrimp sample). AMOZ can be used as a typical marker to monitor drug residues in animal-derived foods in the field of food safety[1][2].
    AMOZ
  • HY-134421
    2-Butenoyl coenzyme A lithium

    		HMG-CoA Reductase (HMGCR) Metabolic Disease
    2-Butenoyl coenzyme A lithium is an inactivator and a substrate of Plasmodium falciparum enoyl-β-hydroxyacyl-acyl carrier protein (ACP) reductase and other enoyl-CoA reductases, and it is also the lithium salt of trans-2-methyl-2-butenoyl coenzyme A. 2-Butenoyl coenzyme A lithium acts on short-chain and medium-chain coenzyme A dehydrogenases as well as glutaryl-CoA dehydrogenase, and shows no activity against wild-type isovaleryl-CoA dehydrogenase. 2-Butenoyl coenzyme A lithium functions as a metabolite in the L-isoleucine catabolic pathway, and can serve as a substrate in the activity assay of 3-ketothiolase. 2-Butenoyl coenzyme A lithium is applicable to research related to 3-ketothiolase deficiency .
    2-Butenoyl coenzyme A lithium
  • HY-159069
    Zymosan (ZM), 95%

    		Toll-like Receptor (TLR) TNF Receptor Connexin Infection Cancer
    Zymosan (ZM), 95% is a yeast cell wall-derived carbohydrate-rich preparation and immunomodulator. Zymosan (ZM), 95% binds to and activates TLR-2, TLR-4, and Dectin-1 receptor to trigger downstream signaling pathways. Zymosan (ZM), 95% upregulates TLR-2, TLR-4, and TNF-α mRNA expression, increases serum TNF-α levels, and stimulates splenocyte number and viability in mice. Zymosan (ZM), 95% attenuates melanoma growth progression, modulates macrophage marker gene expression, and mediates phagocytosis, ROS generation, and cytokine production. Zymosan (ZM), 95% reduces Connexin 43 protein and mRNA levels, inhibits gap junctional intercellular communication, and induces proinflammatory factor production in human corneal cells. Zymosan (ZM), 95% induces peritoneal inflammation in mice, functions as a drug carrier, and supports fibroblast cell attachment in hydrogel formulations. Zymosan (ZM), 95% can be used for the research of melanoma, tumors, fungal keratitis, ocular surface inflammatory disorders, and peritoneal inflammation .
    Zymosan (ZM), 95%
  • HY-W587552
    1,3-Diolein

    		Liposome Endogenous Metabolite
    1,3-Diolein is a phospholipid compound that has the activity of regulating cell membrane fluidity and signal transduction. 1,3-Diolein is widely used in cell biology research to study lipid-mediated signal transduction pathways and membrane protein interactions. 1,3-Diolein can also serve as a functional carrier in compound delivery systems to help improve the bioavailability of compounds.
    1,3-Diolein
  • HY-127146
    Platensimycin

    		Antibiotic Bacterial Infection
    Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0.1 μM). Platensimycin targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
    Platensimycin
  • HY-139410
    Sodium caseinates

    		c-Fms Inflammation/Immunology
    Sodium caseinates is a kind of sodium salts of major milk proteins, which act as protein-based biopolymers and innate immune system activators. Sodium caseinates induce granulopoiesis, activation and differentiation, promote the production of M-CSF, and increase serum levels of G-CSF and GM-CSF. Sodium caseinates inhibit the proliferation and reduce the viability of leukemia macrophage-like cells, thereby significantly improving the survival rate of mice inoculated with leukemia cells. Sodium caseinates can serve as carriers for probiotics in edible films and exhibit anti-Listeria activity. Sodium caseinates effectively protect vitamin A from degradation, enhance its stability, bioaccessibility and bioavailability, and regulate protein digestibility when complexed with vitamin A. Sodium caseinates can be applied to research related to acute monocytic leukemia and vitamin A deficiency .
    Sodium caseinates
  • HY-N6711
    Equisetin

    		HIV Integrase Bacterial Antibiotic Reactive Oxygen Species (ROS) STAT AMPK 11β-HSD Infection Metabolic Disease
    Equisetin is an N-methylserine-derived acyl tetramic acid, quorum sensing inhibitor (QSI), herbicides and antibiotics. Equisetin specifically inhibits the anionic carriers of substrates in the inner mitochondrial membrane. Equisetin inhibits the activity of HIV-1 integrase, 11β-HSD1, and 2,4-dinitrophenol (Dnp)-stimulated ATPase (IC50 = ~8 nmol per mg of protein). Equisetin exhibits growth inhibition of bacteria, anti-inflammatory, amelioration of lipid-associated disorders, and cytotoxic effects .
    Equisetin
  • HY-142980
    DOPG

    Dioleoylphosphatidylglycerol

    		 Liposome Inflammation/Immunology
    DOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion .
    DOPG
  • HY-P10502A
    L57 acetate

    		LDLR Others
    L57 acetate is a Low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 acetate exhibits high affinity to LRP1 with Ki of 45 nM. L57 acetate exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 acetate can be utilized as the carrier for CNS drug delivery .
    L57 acetate
  • HY-149276
    SLC26A3-IN-2
    1 Publications Verification

    		 GLUT Metabolic Disease
    SLC26A3-IN-2 is an orally active inhibitor of anion exchanger protein SLC26A3 (IC50=360 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .
    SLC26A3-IN-2
  • HY-W012166
    N-Succinimidyl bromoacetate

    NHS-Bromoacetate

    		 Biochemical Assay Reagents Infection
    N-Succinimidyl bromoacetate (NHS-Bromoacetate) is a heterobifunctional crosslinking reagent, mainly used to modify the ɛ-amino group of lysine side chains. By covalently linking its bromoacetyl moiety to the ɛ-amino group of lysine in peptidomimetics, N-Succinimidyl bromoacetate enables their conjugation with thiol-modified nanoparticles via thioether bonds. N-Succinimidyl bromoacetate also performs bromoacetylation modification on carrier proteins, which then forms stable thioether bonds with the thiol groups of cysteine in peptides, thus efficiently preparing soluble peptide-protein conjugates with high substitution ratios. N-Succinimidyl bromoacetate can be used to prepare activated Sepharose derivatives for affinity chromatography, protein affinity labeling reagents, and peptide-protein immunogen conjugates with non-immunogenic linkages. N-Succinimidyl bromoacetate is applicable to studies related to HIV-1 infection and glioblastoma multiforme .
    N-Succinimidyl bromoacetate
  • HY-119749
    Diazaborine

    		Bacterial Infection
    Diazaborine is an inhibitor for enoyl-acyl carrier protein (enoyl ACP) in an NAD+-dependent manner. Diazaborine exhibits antibacterial activity, MIC for E. coli and K. pneumoniae is 25 and 3.12 μg/mL .
    Diazaborine
  • HY-P5107
    Low molecular weight protamine

    LMWP; TDSP5

    		 VEGFR Cancer
    Low molecular weight protamine (LMWP;TDSP5) is a truncated arginine-rich protamine peptide, as well as a heparin/low-molecular-weight heparin antidote and a cell-penetrating delivery carrier. Low molecular weight protamine neutralizes heparin-induced anticoagulant activities, including aPTT, anti-Xa and anti-IIa activities, and also neutralizes anti-Xa activity of commercially available low-molecular-weight heparin preparations. Low molecular weight protamine translocates across mammalian cell membranes, delivers conjugated impermeable molecules across tumor tissues, enhances skin permeability of conjugated epidermal growth factor, and accelerates wound healing when conjugated with epidermal growth factor. Low molecular weight protamine retains the in vitro cell proliferation activity of conjugated EGF, and also enables site-specific conjugation with peptides or proteins via genetic recombination. Low molecular weight protamine can be used in studies related to colon adenocarcinoma, skin wounds and diabetic skin wounds .
    Low molecular weight protamine
  • HY-B1884
    Procymidone

    		Fungal Infection Inflammation/Immunology
    Procymidone, a pesticide, is an immunogen hapten that can be combined with cOVA (carrier protein) to produce polyclonal antibodies. Procymidone has antifungal activity .
    Procymidone
  • HY-111071
    Nilofabicin

    CG-400549

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin .
    Nilofabicin
  • HY-W747491
    Triclosan-13C12

    		Isotope-Labeled Compounds Antibiotic Apoptosis Bacterial Fungal Infection Cancer
    Triclosan- 13C12 is 13C labeled Triclosan (HY-B1119). Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
    Triclosan-13C12
  • HY-169838
    WYneC

    		Biochemical Assay Reagents Others
    WYneC can specifically bind to sulfinylated proteins in living cells and then react with fluorescent probes containing azide groups for detection. In the field of redox biology, WYneC can also be used to determine the occupancy of S-sulfinylation sites or as a carrier to deliver substances to mitochondria .
    WYneC
  • HY-P2995A
    Hemoglobin porcine

    		Biochemical Assay Reagents Others
    Hemoglobin porcine is an oxygen-transporting protein present in the blood of domestic pigs, and also an oxygen carrier with higher oxygen affinity than human hemoglobin. Hemoglobin porcine exhibits cooperative oxygen-binding properties, with weaker heme-heme interactions than those of human hemoglobin .
    Hemoglobin porcine
  • HY-122658
    MitoBloCK-1

    MB-1

    		 Mitochondrial Metabolism Metabolic Disease
    MitoBloCK-1 (MB-1) is an inhibitor that blocks the import of substrates that use the TIM22 import pathway. MitoBloCK-1 inhibits import by preventing binding of substrate to tim9/10 complex to the substrate, thus the substrate failed to be reach the TIM22 translocon. MitoBloCK-1 inhibits protein import of TIM22 substrates into mitochondria. MitoBloCK-1 attenuates the import of the carrier proteins including the ADP/ATP and phosphate carriers. MitoBloCK-1 also inhibits the import of an additional carrier protein, PiC, and the outer membrane protein Tom40 .
    MitoBloCK-1
  • HY-W653962
    Triclosan-13C6

    		Isotope-Labeled Compounds Apoptosis Antibiotic Fungal Bacterial Infection Cancer
    Triclosan- 13C6 is 13C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
    Triclosan-13C6
  • HY-178914
    Copper ionophore I

    		Cuproptosis Reactive Oxygen Species (ROS) Mitochondrial Metabolism Cancer
    Copper ionophore I is an efficient copper ion carrier. Copper ionophore I can regulate various intracellular copper levels to induce cuproptosis, such as 4T1 (IC50 = 0.45 μM) and MDA-MB-231(IC50 = 1.21 μM) cells. Copper ionophore I can induce an increase in ROS and cause mitochondrial dysfunction. Copper ionophore I can reduce the expression of FDX1, DLAT, and LIAS proteins. Copper ionophore I can activate immune related pathways and promote T cell infiltration. Copper ionophore I can be used for cancer research .
    Copper ionophore I
  • HY-B1119R
    Triclosan (Standard)

    		Reference Standards Bacterial Fungal Antibiotic Apoptosis Infection Cancer
    Triclosan (Standard) is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
    Triclosan (Standard)
  • HY-W046063
    O-Phthalimide-C3-acid

    4-Phthalimidobutyric acid

    		 Biochemical Assay Reagents Inflammation/Immunology
    4-(N-Phthalimidoyl)butanoic acid (compound FB) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 4-(N-Phthalimidoyl)butanoic acid can be combined with carrier proteins and used in antigen design .
    O-Phthalimide-C3-acid
  • HY-P10680
    TFE-IDAtp1-LinA

    		Liposome Others
    TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED50 of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .
    TFE-IDAtp1-LinA
  • HY-157194
    RL-6-Me-7-OH

    		Biochemical Assay Reagents Inflammation/Immunology
    RL-6-Me-7-OH is a hapten that activates human and mouse MAIT cells (EC50 = 25 µM). RL-6-Me-7-OH can be combined with carrier proteins and used in antigen design. RL-6-Me-7-OH can be used in inflammation and immunity research .
    RL-6-Me-7-OH
  • HY-P99913
    Eflapegrastim

    		c-Fms Inflammation/Immunology Cancer
    Eflapegrastim is a composite protein consisting of a genetically modified granulocyte-colony stimulating factor (GCSF) molecule linked via a chemical bond to an IgG4 Fc fragment (LAPS-carrier). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia .
    Eflapegrastim
  • HY-N15742
    Talaroconvolutin A

    		Ferroptosis Reactive Oxygen Species (ROS) p38 MAPK Cancer
    Talaroconvolutin A is a ferroptosis inducer. Talaroconvolutin A induces ferroptosis by increasing reactive oxygen species (ROS) levels rather than the GPX4 pathway. Talaroconvolutin A downregulates the expression of the channel protein solute carrier family 7 member 11 (SLC7A11) and upregulates arachidonic acid lipoxygenase 3 (ALOXE3). Talaroconvolutin A inhibits the growth of colorectal cancer cells HCT116 and bladder cancer cells SW480 with IC50 values of 1.22 μM and 1.4 μM, respectively. Talaroconvolutin A can be used in the study of colorectal cancer and bladder cancer [1] [2] [3].
    Talaroconvolutin A
  • HY-113225B
    Guanosine triphosphate tritris

    GTP tritris

    		 Endogenous Metabolite Exosomes Cancer
    Guanosine triphosphate tritris (GTP tritris) serves as a vital enhancer of myogenic cell differentiation and plays a critical role in modulating miRNA-myogenic regulator factors. It also facilitates the release of exosomes enriched with guanosine and guanosine-derived molecules, and is regarded as an activated precursor for RNA synthesis. In mitochondrial function, GTP participates in the import of proteins into the matrix, which is essential for various regulated pathways, and is involved in initiating peptide synthesis through the binding of formylmethionyl-tRNA to the ribosome, as well as polypeptide chain elongation. Additionally, GTP acts as a phosphate and pyrophosphate carrier that channels chemical energy into specific biosynthetic pathways. It activates signal transducing G proteins that regulate cellular processes such as proliferation and differentiation, and its hydrolysis by small GTPases, including Ras and Rho, is integral to both proliferation and apoptosis. Furthermore, the small GTPase Rab is instrumental in vesicle docking, fusion, and formation. Beyond signal transduction, GTP is an energy-rich precursor in the enzymatic biosynthesis of DNA and RNA.
    Guanosine triphosphate tritris
  • HY-155852
    Lepadin H

    		Ferroptosis Apoptosis ACSL Family Glutathione Peroxidase Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Lepadin H is a ferroptosis inducer and apoptosis inducer with in vitro cytotoxicity and in vivo antitumor efficacy against cancer cells. Lepadin H reduces GPX4 and SLC7A11 levels, increases p53 and ACSL4 expression, drives lipid hydroperoxide production, elevates reactive oxygen species (ROS) levels, reduces cellular glutathione (GSH) levels, induces lipid peroxidation and G2/M phase cell cycle arrest, and suppresses clonogenic growth and migration of cancer cells.Lepadin H can be used for the research of melanoma .
    Lepadin H
  • HY-120884
    InhA-IN-5

    		Bacterial Infection
    InhA-IN-5 (compound 1) is a potent Mycobacterial tuberculosis (Mtb) trans-2-enoyl-acyl carrier protein reductase (InhA) inhibitor .
    InhA-IN-5
  • HY-149751
    Methylthiomcresol-C5-COOH

    		Biochemical Assay Reagents Others
    Methylthiomcresol-C5-COOH (Compound F4) is a hapten that can be conjugated to carrier proteins for antigen design. Methylthiomcresol-C5-COOH designed antigen can be applied in ELISA to detect the residual amount of fenthion in white wine samples .
    Methylthiomcresol-C5-COOH
  • HY-149749
    Methylthiomcresol-C3-COOH

    		Biochemical Assay Reagents Others
    Methylthiomcresol-C3-COOH (Compound F2) is a hapten that can be conjugated to carrier proteins for antigen design. Methylthiomcresol-C3-COOH designed antigen can be applied in ELISA to detect the residual amount of fenthion in white wine samples .
    Methylthiomcresol-C3-COOH
  • HY-D2857
    NBD-Stearic acid

    		Fluorescent Dye Metabolic Disease
    NBD-Stearic acid is a stearic acid labeled with a nitrobenzoxadiazole (NBD) fluorophore. NBD-Stearic acid can be used as a probe for fatty acid uptake or the the ligand binding sites of fatty acid and sterol carrier proteins (FABP)
    NBD-Stearic acid
  • HY-157174
    Mannosamine–desthiobiotin adduct

    		Others Inflammation/Immunology
    Mannosamine-desthiobiotin adduct (compound MDTBA) is a carrier immunogenicity-reducing hapten that reduces the immunogenicity of protein carriers upon conjugation to available free amines on the carrier protein surface. Conjugation of Mannosamine-desthiobiotin adduct to hsIgG significantly (>1-fold) reduced the immunogenicity of hsIgG. Mannosamine-desthiobiotin adduct can be used in antigen design research .
    Mannosamine–desthiobiotin adduct
  • HY-N15885
    12-NBD Stearate

    		Fluorescent Dye FABP Phosphatase Metabolic Disease
    12-NBD Stearate is a fluorescent fatty acid analogue. 12-NBD Stearate binds to fatty acid binding protein (FABP) and sterol carrier protein-2 (SCP-2). Overexpressing sterol carrier protein-2 (SCP-2) 15-kDa isoform enhances 12-NBD Stearate transport. 12-NBD Stearate is a tool for microscopic long chain fatty acids (LCFA) uptake and internalization studies .
    12-NBD Stearate
  • HY-157187
    Fenhexamid-1-pentanoic acid

    		Biochemical Assay Reagents Others
    Fenhexamid-1-pentanoic acid is a hapten that can be covalently coupled to a carrier protein for the determination of cyclohexamide residues .
    Fenhexamid-1-pentanoic acid
  • HY-157183
    HSMO9

    		Biochemical Assay Reagents Inflammation/Immunology
    HSMO9 is a (+)-methamphetamine (METH)-like hapten that can be coupled to a carrier protein. HSMO9 can be used in vaccine development .
    HSMO9

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