DPhPC
Based on 1 Customer Validation
DPhPC is a phospholipid compound characterized by high mechanical and chemical stability, broad temperature phase stability, and high electrical resistance. DPhPC readily forms unilamellar vesicles and solid-supported bilayers. DPhPC is commonly used as a component of nanoliposomal drug carriers or as a model membrane material for studies on membrane proteins/ion channels.
For research use only. We do not sell to patients.
- Purity : 99.77%
- CAS No.: 207131-40-6
- Formula: C48H96NO8P
- Molecular Weight:846.25
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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(Z)-(R)-3-(Phosphonooxy)propane-1,2-diyl dioleate sodium salt -
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DOPG sodium
Biological Activity
Description
In Vitro
DPhPC is the core phospholipid component for constructing nitroglycerin nanoliposomes, which enables the effective encapsulation of nitroglycerin by virtue of its amphipathic property and facilitates the efficient uptake of nanoliposomes by endothelial cells. The nanoliposomes prepared on the basis of DPhPC can improve the bioavailability of nitric oxide and exert anti-inflammatory effects[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 207131-40-6
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Appearance Oil
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Molecular Weight 846.25
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Formula C48H96NO8P
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Color Colorless to light yellow
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SMILES
CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
Ethanol : 50 mg/mL (59.08 mM; Need ultrasonic)
DMSO : 3.57 mg/mL (4.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (645 KB)
- English - EN (645 KB)
- Français - FR (645 KB)
- Deutsch - DE (645 KB)
- Norwegian - NO (645 KB)
- Español - ES (645 KB)
- Swedish - SV (645 KB)
- Italian - IT (645 KB)
- Korean - KR (645 KB)
- Portuguese - PT (645 KB)
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Handling Instructions (2659 KB)
References
[1]. Schmidt D, et, al. A gating model for the archeal voltage-dependent K(+) channel KvAP in DPhPC and POPE:POPG decane lipid bilayers. J Mol Biol. 2009 Jul 31;390(5):902-12. [Content Brief]
[2]. Andersson M, et, al. Vesicle and bilayer formation of diphytanoylphosphatidylcholine (DPhPC) and diphytanoylphosphatidylethanolamine (DPhPE) mixtures and their bilayers' electrical stability. Colloids Surf B Biointerfaces. 2011 Feb 1;82(2):550-61. [Content Brief]
[3]. Ardekani S, et al. Nanoliposomal nitroglycerin exerts potent anti-inflammatory effects[J]. Scientific reports, 2015, 5(1): 16258. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol | 1 mM | 1.1817 mL | 5.9084 mL | 11.8168 mL | 29.5421 mL |
| Ethanol | 5 mM | 0.2363 mL | 1.1817 mL | 2.3634 mL | 5.9084 mL |
| 10 mM | 0.1182 mL | 0.5908 mL | 1.1817 mL | 2.9542 mL | |
| 15 mM | 0.0788 mL | 0.3939 mL | 0.7878 mL | 1.9695 mL | |
| 20 mM | 0.0591 mL | 0.2954 mL | 0.5908 mL | 1.4771 mL | |
| 25 mM | 0.0473 mL | 0.2363 mL | 0.4727 mL | 1.1817 mL | |
| 30 mM | 0.0394 mL | 0.1969 mL | 0.3939 mL | 0.9847 mL | |
| 40 mM | 0.0295 mL | 0.1477 mL | 0.2954 mL | 0.7386 mL | |
| 50 mM | 0.0236 mL | 0.1182 mL | 0.2363 mL | 0.5908 mL |
DPhPC Related Classifications
HY-143202 Related Classifications
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