Cytochrome C (equine heart)
Based on 1 Customer Validation
Cytochrome C (equine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (equine heart) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (equine heart) can act as a single electron carrier.
For research use only. We do not sell to patients.
- Purity: 99.1%
- CAS No.: 9007-43-6
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Mammalian Cytochrome C scavenges reactive oxygen species (ROS) under healthy conditions, produces ROS with the co-factor p66Shc, and oxidizes cardiolipin during apoptosis[1].
Cytochrome C (equine heart) spontaneously forms thioether bonds with hemoglobin in vitro[2].
Cytochrome C (equine heart) is released from the intermembrane space of the mitochondria into the cytoplasm when the cell receives an apoptotic signal. In the cytoplasm, it no longer performs its normal respiratory function but instead acts as a crucial apoptotic signaling molecule, binding to apoptotic protease activating factor-1 (APAF-1), initiating the caspase cascade reaction, and ultimately leading to cell apoptosis[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9007-43-6
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Appearance Solid
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Color Brown to reddish brown
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SMILES
[Cytochrome C (equine heart)]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
H2O : 16.67 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Hüttemann M, et al. The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis. Mitochondrion. 2011 May;11(3):369-81. [Content Brief]
[2]. Daltrop O, Ferguson SJ. Cytochrome c maturation. The in vitro reactions of horse heart apocytochrome c and Paracoccus dentrificans apocytochrome c550 with heme. J Biol Chem. 2003 Feb 14;278(7):4404-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cytochrome C (equine heart) Related Classifications
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