1,3-Diolein
Based on 1 Customer Validation
1,3-Diolein is a phospholipid compound that has the activity of regulating cell membrane fluidity and signal transduction. 1,3-Diolein is widely used in cell biology research to study lipid-mediated signal transduction pathways and membrane protein interactions. 1,3-Diolein can also serve as a functional carrier in compound delivery systems to help improve the bioavailability of compounds.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 2465-32-9
- Formula: C39H72O5
- Molecular Weight:620.99
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 7
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Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
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[PMID: 28445049] |
| HepG2 | IC50 |
>10 μM
Compound: 7
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
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[PMID: 28445049] |
| MDA-MB-231 | IC50 |
>10 μM
Compound: 7
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Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
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[PMID: 28445049] |
| Neutrophil | IC50 |
>10 μM
Compound: 7
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Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced elastase release by measuring degranulation of azurophilic granules using MeOSuc-Ala-Ala-ProVal-p-nitroanilide as substrate preincubated for 5 mins followed by CB/fM
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced elastase release by measuring degranulation of azurophilic granules using MeOSuc-Ala-Ala-ProVal-p-nitroanilide as substrate preincubated for 5 mins followed by CB/fM
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[PMID: 28445049] |
| Neutrophil | IC50 |
>10 μM
Compound: 7
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Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced superoxide anion generation preincubated for 5 mins followed by CB stimulation for 3 mins and subsequent fMLF stimulation for 10 mins by spectrophotometric method
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced superoxide anion generation preincubated for 5 mins followed by CB stimulation for 3 mins and subsequent fMLF stimulation for 10 mins by spectrophotometric method
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[PMID: 28445049] |
Chemical Information
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CAS No. 2465-32-9
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Appearance Viscous liquid
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Molecular Weight 620.99
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Formula C39H72O5
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Color Colorless to light yellow
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SMILES
CCCCCCCC/C=C\CCCCCCCC(OCC(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (161.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (236 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6103 mL | 8.0517 mL | 16.1033 mL | 40.2583 mL |
| 5 mM | 0.3221 mL | 1.6103 mL | 3.2207 mL | 8.0517 mL | |
| 10 mM | 0.1610 mL | 0.8052 mL | 1.6103 mL | 4.0258 mL | |
| 15 mM | 0.1074 mL | 0.5368 mL | 1.0736 mL | 2.6839 mL | |
| 20 mM | 0.0805 mL | 0.4026 mL | 0.8052 mL | 2.0129 mL | |
| 25 mM | 0.0644 mL | 0.3221 mL | 0.6441 mL | 1.6103 mL | |
| 30 mM | 0.0537 mL | 0.2684 mL | 0.5368 mL | 1.3419 mL | |
| 40 mM | 0.0403 mL | 0.2013 mL | 0.4026 mL | 1.0065 mL | |
| 50 mM | 0.0322 mL | 0.1610 mL | 0.3221 mL | 0.8052 mL | |
| 60 mM | 0.0268 mL | 0.1342 mL | 0.2684 mL | 0.6710 mL | |
| 80 mM | 0.0201 mL | 0.1006 mL | 0.2013 mL | 0.5032 mL | |
| 100 mM | 0.0161 mL | 0.0805 mL | 0.1610 mL | 0.4026 mL |
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