1,3-Diolein

Cat. No.: HY-W587552 Purity: 99.95%: Data Sheet
COA

SDS
Handling Instructions
FAQs
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1,3-Diolein is a phospholipid compound that has the activity of regulating cell membrane fluidity and signal transduction. 1,3-Diolein is widely used in cell biology research to study lipid-mediated signal transduction pathways and membrane protein interactions. 1,3-Diolein can also serve as a functional carrier in compound delivery systems to help improve the bioavailability of compounds.

For research use only. We do not sell to patients.

1,3-Diolein Chemical Structure

CAS No. : 2465-32-9

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Other Forms of 1,3-Diolein:

1,3-Dioleoylglycerol-d₅ Get quote
1,3-Diolein-d₆₆ Get quote

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Human Endogenous Metabolite Microbial Metabolite

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Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	> 10 μM Compound: 7	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28445049]
HepG2	IC₅₀	> 10 μM Compound: 7	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28445049]
MDA-MB-231	IC₅₀	> 10 μM Compound: 7	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28445049]
Neutrophil	IC₅₀	> 10 μM Compound: 7	Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced elastase release by measuring degranulation of azurophilic granules using MeOSuc-Ala-Ala-ProVal-p-nitroanilide as substrate preincubated for 5 mins followed by CB/fMLF stimulation Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced elastase release by measuring degranulation of azurophilic granules using MeOSuc-Ala-Ala-ProVal-p-nitroanilide as substrate preincubated for 5 mins followed by CB/fMLF stimulation	[PMID: 28445049]
Neutrophil	IC₅₀	> 10 μM Compound: 7	Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced superoxide anion generation preincubated for 5 mins followed by CB stimulation for 3 mins and subsequent fMLF stimulation for 10 mins by spectrophotometric method Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced superoxide anion generation preincubated for 5 mins followed by CB stimulation for 3 mins and subsequent fMLF stimulation for 10 mins by spectrophotometric method	[PMID: 28445049]

Molecular Weight

620.99

Formula

C₃₉H₇₂O₅

CAS No.

2465-32-9

Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

CCCCCCCC/C=C\CCCCCCCC(OCC(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (161.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6103 mL	8.0517 mL	16.1033 mL
5 mM	0.3221 mL	1.6103 mL	3.2207 mL
10 mM	0.1610 mL	0.8052 mL	1.6103 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

Select Batch:

Data Sheet (236 KB) SDS (393 KB)

COA (237 KB) HNMR (282 KB) RP-HPLC (240 KB) MS (68 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6103 mL	8.0517 mL	16.1033 mL	40.2583 mL
	5 mM	0.3221 mL	1.6103 mL	3.2207 mL	8.0517 mL
	10 mM	0.1610 mL	0.8052 mL	1.6103 mL	4.0258 mL
	15 mM	0.1074 mL	0.5368 mL	1.0736 mL	2.6839 mL
	20 mM	0.0805 mL	0.4026 mL	0.8052 mL	2.0129 mL
	25 mM	0.0644 mL	0.3221 mL	0.6441 mL	1.6103 mL
	30 mM	0.0537 mL	0.2684 mL	0.5368 mL	1.3419 mL
	40 mM	0.0403 mL	0.2013 mL	0.4026 mL	1.0065 mL
	50 mM	0.0322 mL	0.1610 mL	0.3221 mL	0.8052 mL
	60 mM	0.0268 mL	0.1342 mL	0.2684 mL	0.6710 mL
	80 mM	0.0201 mL	0.1006 mL	0.2013 mL	0.5032 mL
	100 mM	0.0161 mL	0.0805 mL	0.1610 mL	0.4026 mL

1,3-Diolein Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,3-Diolein2465-32-9LiposomeEndogenous MetaboliteInhibitorinhibitorinhibit

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1,3-Diolein

Other Forms of 1,3-Diolein:

1,3-Diolein Related Antibodies

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Biological Activity

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