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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
cholesterol absorption inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "cholesterol absorption inhibitor" in MCE Product Catalog:
16
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Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
2
2 Cited Publications
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Phosphatidylcholines, egg are a type of phosphatidylcholine that can be isolated and extracted from eggs, primarily present in egg yolks. As a major phospholipid component of cell membranes, Phosphatidylcholines, egg play a key role in providing nutrition and protection to the body. Phosphatidylcholines, egg can inhibit oxidative stress and neurotoxicity, exerting neuroprotective effects. Additionally, Phosphatidylcholines, egg can suppress the lymphatic absorption of cholesterol in the intestine and are also used in research on intestinal lipid absorption .
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2 Cited Publications
Synonyms: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide
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Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity . Ezetimibe is a potent cholesterol absorption inhibitor .
Synonyms: AC 223; DL-N-(α-Methylbenzyl)linoleamide
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Melinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC50 of 20.9 μM.
Cat. No.: HY-119220
CAS No.: 594842-13-4
Synonyms: JTT-130
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Granotapide is an orally active microsomal triglyceride transfer protein (MTP) inhibitor. Granotapide reduces the absorption of cholesterol and triglycerides by inhibiting MTP. Granotapide can be used in the research of coronary artery disease, obesity, diabetes mellitus and hypertension .
Cat. No.: HY-136059
CAS No.: 302781-98-2
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Desfluoro-ezetimibe is a desfluoro impurity of Ezetimibe. Ezetimibe is a potent, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator .
Cat. No.: HY-17376S1
CAS No.: 1093659-89-2
Synonyms: SCH 58235-d4-1
Cat. No.: HY-17376R
CAS No.: 163222-33-1
Synonyms: SCH 58235 (Standard)
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Ezetimibe (Standard) is the analytical standard of Ezetimibe. This product is intended for research and analytical applications. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
Cat. No.: HY-17376S
CAS No.: 1093659-90-5
Synonyms: SCH 58235-d4
Cat. No.: HY-45131
CAS No.: 190595-65-4
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Cholesterol absorption inhibitor 1 (compound 21) is a cholesterol absorption inhibitor that reduces liver cholesteryl ester .
Cat. No.: HY-129344
CAS No.: 96224-26-9
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CL 277082 is a potent and selective acyl CoA:cholesterol acyltransferase (ACAT) inhibitor in microsomes. CL 277082 inhibits ACAT with IC50 values of 0.14 μM for intestinal mucosal microsomes, 0.74 μM for liver, and 1.18 μM for rat adrenal. CL 277082 is a ACAT-catalyzed cholesterol esterification and cholesterol absorption inhibitor .
Cat. No.: HY-P10342
CAS No.: 510725-34-5
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Cat. No.: HY-107176A
CAS No.: 1266548-74-6
Synonyms: HS-25
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Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys .
Cat. No.: HY-135391S
CAS No.: 1426174-41-5
Synonyms: Ezetimibe glucuronide-d4; Ezetimibe β-D-glucuronide-d4
Cat. No.: HY-19251
CAS No.: 107376-72-7
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CL-283796 is a potent and orally active acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. CL-283796 reduces low-density lipoprotein (LDL) cholesterol without affecting cholesterol absorption in African green monkeys. CL-283796 can be used for hypercholesterolemia research .
Cat. No.: HY-135388
CAS No.: 1376614-99-1
Synonyms: ent-SCH 58235
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ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator .
Cat. No.: HY-106106
CAS No.: 99759-19-0
Synonyms: CP‐88,818; β‐Tigogenin cellobioside
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Tiqueside (CP‐88,818) is an orally active cholesterol absorption inhibitor. Tiqueside inhibits absorption of both dietary cholesterol and endogenous cholesterol excreted into the intestinal lumen via the bile. Tiqueside can be used in the research of hypercholesterolemia .
Cat. No.: HY-19497
CAS No.: 768394-99-6
Synonyms: AVE-5530; BART-1741
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Canosimibe is a cholesterol absorption inhibitor extracted from patent WO2004087655A1.
Cat. No.: HY-106902
CAS No.: 162490-89-3
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F-1394 is an orally active acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor that inhibits dietary cholesterol absorption in mice. F-1394 can be used in cardiovascular disease research .
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Diethylumbelliferyl phosphate (DEUP), a selective and potent inhibitor of cholesterol esterase, does not inhibit protein kinase activity A in vitro, and it effectively disrupts steroidogenesis by blocking the transport of cholesterol into the mitochondria of steroidogenic cells, with an IC50 of 11.6 μM, potentially limiting dietary cholesterol absorption.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
