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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
cis-trans prolyl isomerase
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "cis-trans prolyl isomerase" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P70007A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding Protein Li 69p; Peptidylprolyl isomerase A; Peptidylprolyl isomerase A (Cyclophilin A); CYPA; Peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding Pr
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor (API-1) with an IC50 of 72.3 nM. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase (PPIase) domain and potently inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development .
1
1 Cited Publications
Cat. No.: HY-P71224
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPID; PPIase D; Peptidylprolyl isomerase D; 40 KDa Peptidyl-prolyl cis-trans isomerase D; CYP-40; Peptidylprolyl isomerase D (Cyclophilin D); Peptidyl-prolyl cis-trans isomerase D; Peptidyl-prolyl cis-trans isomerase; Rotamase D; Testicular Tissue Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-P4581
CAS No.: 128802-78-8
Synonyms: Suc-ALPF-pNA
Cat. No.: HY-164895
CAS No.: 3080918-50-6
PIN1 degrader-1 is a covalent PIN1 degrader with an IC50 of 21.5 nM. PIN1 degrader-1 induces a decrease in the thermal stability of PIN1, and triggers PIN1 degradation in a concentration- and time-dependent manner across various cancer cells. PIN1 degrader-1 also reduces the viability of pancreatic cancer, breast cancer, prostate cancer and lung cancer cells. PIN1 degrader-1 can be used for research on pancreatic cancer, breast cancer, prostate cancer and non-small cell lung cancer .
Cat. No.: HY-P71224A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPID; PPIase D; Peptidylprolyl isomerase D; 40 KDa Peptidyl-prolyl cis-trans isomerase D; CYP-40; Peptidylprolyl isomerase D (Cyclophilin D); Peptidyl-prolyl cis-trans isomerase D; Peptidyl-prolyl cis-trans isomerase; Rotamase D; Testicular Tissue Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-P70047A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding Protein Li 69p; Peptidylprolyl isomerase A; Peptidylprolyl isomerase A (Cyclophilin A); CYPA; Peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding Pr
Species:
Human
Source:
E. coli
Cat. No.: HY-125182
CAS No.: 2649904-85-6
Target:
Research Areas:
SMCypI C31 is a non-peptidic cyclophilin inhibitor with potent peptidyl-prolyl cis/trans isomerases (PPIase) inhibitory activity (IC50 of 0.1 µM). SMCypI C31 shows pangenotype anti-HCV activity with EC50s ranging from 1.20 to 7.76 μM for genotype 1a, 1b, 2a, 3a, and 5a HCV subgenomic replicons (HCV-SGRs) and chimeric genotype 2a/4a HCV-SGRs. SMCypI C31 disrupts the cyclophilin A-NS5A interaction .
Cat. No.: HY-P87986
Synonyms: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Parvulin-14, Parvulin-17, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis/trans isomerase EPVH, Rotamase Pin4, Par14, hPar14, Par17, hPar17, PPIase Pin4, hEPVH, PIN4
Cat. No.: HY-P70047
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding Protein Li 69p; Peptidylprolyl isomerase A; Peptidylprolyl isomerase A (Cyclophilin A); CYPA; Peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding Protein; HEL-S-69p; Cyclophilin A; PPIase; Rotamase A; CYPH; PPIase A
Species:
Human
Source:
E. coli
Cat. No.: HY-12135
CAS No.: 1239513-63-3
Target:
Research Areas:
Poloxipan is a pan-specific polo-like kinase (PLK) inhibitor that can inhibit a non-catalytic region at the C-terminus called the Polo-box domain (PBD) found in kinases. The IC50 values for Poloxipan against the PBDs of PLK-1/2/3 are 3.2 μM, 1.7 μM, and 3.0 μM, respectively. Poloxipan also inhibits other phospho-tyrosine binding domains, such as the forkhead-associated (FHA) domain of CHK-2, the WW domain of peptidyl-prolyl cis/trans isomerase (PIN1), and the phospho-tyrosine binding domains of STAT1/3/5 and lymphocyte-specific protein tyrosine kinase's SH2 domain. Poloxipan can be used in cancer research .
Cat. No.: HY-P74212
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding Protein Li 69p; Peptidylprolyl isomerase A; Peptidylprolyl isomerase A (Cyclophilin A); CYPA; Peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding Pr
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P74211A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIF; HCyP3; Peptidylprolyl isomerase F; CyP-M; CypD; CYP3; Cyclophilin D; Peptidyl-prolyl cis-trans isomerase, Mitochondrial; Cyp-D; Peptidylprolyl isomerase F (Cyclophilin F); Peptidyl-prolyl cis-trans isomerase F, Mitochondrial; Peptidyl-prolyl cis-Tra
Species:
Human
Source:
HEK293
Cat. No.: HY-P71501
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding Protein Li 69p; Peptidylprolyl isomerase A; Peptidylprolyl isomerase A (Cyclophilin A); CYPA; Peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding Pr
Species:
E.coli
Source:
E. coli
Cat. No.: HY-P74211
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPIF; HCyP3; Peptidylprolyl isomerase F; CyP-M; CypD; CYP3; Cyclophilin D; Peptidyl-prolyl cis-trans isomerase, Mitochondrial; Cyp-D; Peptidylprolyl isomerase F (Cyclophilin F); Peptidyl-prolyl cis-trans isomerase F, Mitochondrial; Peptidyl-prolyl cis-Tra
Species:
Human
Source:
HEK293
Cat. No.: HY-P70333
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FKBP2; Proline isomerase; FKBP prolyl isomerase 2; PPIase FKBP2; FKBP-13; 13 KDa FKBP; FKBP13; Rotamase; PPIase; Epididymis Secretory Sperm Binding Protein; Peptidyl-prolyl cis-trans isomerase FKBP2; Peptidyl-prolyl cis-trans isomerase; FK506 Binding Prot
Species:
Human
Source:
HEK293
Cat. No.: HY-P811880
Synonyms: CYPC, PPIC, Peptidyl-prolyl cis-trans isomerase C, PPIase C, Cyclophilin C, Rotamase C
Cat. No.: HY-P71225
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIE; MGC111222; Peptidylprolyl isomerase E; MGC3736; Peptidyl-prolyl cis-trans isomerase E; CYP33; Rotamase E; Peptidylprolyl isomerase E (Cyclophilin E); PPIase E; Peptidylprolyl isomerase E, Isoform 1; CyP-33; Peptidyl-prolyl cis-trans isomerase; CypE; Cyclophilin 33; Cyclophilin-33; PPIase; Cyclophilin E
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
