8 Results for "

decompensated

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "decompensated" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-14181
CAS No.: 329773-35-5
Purity:  99.73%
Synonyms: BAY 58-2667
Target:  

Guanylate Cyclase

Research Areas:  

Cardiovascular Disease

Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure.
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3
3 Cited Publications
Cat. No.: HY-P2141
CAS No.: 1234510-46-3
Synonyms: TRV027
Research Areas:  

Cardiovascular Disease

TRV120027, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling . TRV120027 induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling, promotes the formation of a macromolecular complex composed of AT1R-β-arrestin-1-TRPC3-PLCγ at the plasma membrane. TRV120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 has the potential for the acute decompensated heart failure (ADHF) treatment .
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3
3 Cited Publications
Cat. No.: HY-P2141A
Research Areas:  

Cardiovascular Disease

TRV120027 TFA, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages ?-arrestins while blocking G-protein signaling . TRV120027?TFA induces?acute?catecholamine?secretion?through cation channel subfamily C3 (TRPC3) coupling, promotes the formation of a macromolecular complex composed of AT1R–β-arrestin-1–TRPC3–PLCγ at the plasma membrane. TRV120027 TFA inhibits angiotensin II–mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 TFA has the potential for the?acute decompensated heart failure (ADHF) treatment .
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2
2 Cited Publications
Cat. No.: HY-14286
CAS No.: 141505-33-1
Purity:  99.82%
Synonyms: Simsndan; OR-1259
Levosimendan (Simsndan; OR-1259) is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.
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Cat. No.: HY-W016798
CAS No.: 4033-40-3
(S)-2-acetamido-4-amino-4-oxobutanoic acid is a metabolite. (S)-2-acetamido-4-amino-4-oxobutanoic acid can be used in the research of decompensated liver cirrhosis .
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Cat. No.: HY-14286R
CAS No.: 141505-33-1
Synonyms: Simsndan (Standard); OR-1259 (Standard)
Levosimendan (Standard) is the analytical standard of Levosimendan. This product is intended for research and analytical applications. Levosimendan (Simsndan; OR-1259) is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.
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Cat. No.: HY-14181R
CAS No.: 329773-35-5
Synonyms: BAY 58-2667 (Standard)
Cinaciguat (Standard) is the analytical standard of Cinaciguat. This product is intended for research and analytical applications. Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure.
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Cat. No.: HY-W016798R
CAS No.: 4033-40-3
(S)-2-acetamido-4-amino-4-oxobutanoic acid (Standard) is an analytical standard for (S)-2-acetamido-4-amino-4-oxobutanoic acid (HY-W016798). This product is intended for research and analytical applications. (S)-2-acetamido-4-amino-4-oxobutanoic acid is a metabolite. (S)-2-acetamido-4-amino-4-oxobutanoic acid can be used in the research of decompensated liver cirrhosis.
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