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ent-Kaurane diterpenoid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (1) Keap1-Nrf2 (1) NO Synthase (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2113

Glaucocalyxin B 1 Publications Verification	Autophagy	Cancer
Glaucocalyxin B is an ent kaurane diterpenoid isolated from the Chinese traditional medicine Rabdosia japonica with anticancer and antitumor activity; decreases the growth of HL-60 cells with an IC₅₀ of approximately 5.86 μM at 24 h.

HY-N10643

Lushanrubescensin H Rabdoternin H	Others	Others
Lushanrubescensin H (Rabdoternin H) is an ent-Kaurane diterpenoid from Isodon ternifolius aboveground part .

HY-122946

Pterisolic acid B	Keap1-Nrf2	Others
Pterisolic acid B (Compound 2) is an ent-Kaurane diterpenoid. Pterisolic acid B can be isolated from fern Pteris semipinnata (Pteridaceae) .

HY-N16642

Rabdoternin D	Others	Cancer
Rabdoternin D is an Ent-Kaurane diterpenoid found in Rabdosia rubescens. Rabdoternin D shows no significant cytotoxicity to Hep G2, COLO 205, MCF-7 and HL-60 cancer cells with IC₅₀ values >100 μM .

HY-N11049

Xerophilusin A	Others	Others
Xerophilusin A, a ent-kaurane diterpenoid, can be isolated from the aerial parts of Isodon enanderianus .

HY-N8555

ent-Kaurane-16β,19,20-triol	Others	Others
ent-Kaurane-16β,19,20-triol is a Diterpenoids product that can be isolated from the herbs of Euphorbia ehracteolata .

HY-N8494

ent-Kauran-17,19-dioic acid	Others	Others
ent-Kauran-17,19-dioic acid (16α-Hydro-ent-kauran-17,19-dioic acid) is an ent-kaurane diterpenoid .

HY-N10046

ent-17-Hydroxykauran-3-one ent-Kaurane-3-oxo-17β-ol	Others	Others
ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana .

HY-N16817

Rabdoternin E	NO Synthase	Inflammation/Immunology Cancer
Rabdoternin E is a potential anti-inflammatory and antitumor agent. 2α-Acetoxy-14,15-cyclopimara-7β,16-diol only inhibits nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW264.7 macrophages (IC₅₀=2.3 μM) and exhibits cytotoxicity against human tumor cells such as HL-60 and SW-480 (IC₅₀ values ??of 2.6 μM and 4.1 μM, respectively). Rabdoternin E is an ent-kaurane-type diterpenoid compound that can be naturally extracted from the 70% acetone aqueous extract of the aerial parts of Isodon rosthornii (Diels) Hara (a plant of the Lamiaceae family, Isodon genus) .

Glaucocalyxin B 1 Publications Verification	Classification of Application Fields Terpenoids Labiatae Sesquiterpenes Plants Glycyrrhiza lepidota Pursh Disease Research Fields Source Classification Cancer	Autophagy
Glaucocalyxin B is an ent kaurane diterpenoid isolated from the Chinese traditional medicine Rabdosia japonica with anticancer and antitumor activity; decreases the growth of HL-60 cells with an IC₅₀ of approximately 5.86 μM at 24 h.

Lushanrubescensin H Rabdoternin H	Senegalia pennata (L.) Maslin Labiatae Plants	Others
Lushanrubescensin H (Rabdoternin H) is an ent-Kaurane diterpenoid from Isodon ternifolius aboveground part .

Pterisolic acid B	Terpenoids Pteridaceae Diterpenoids Plants Pteris semipinnata L. Sp. Source Classification	Keap1-Nrf2
Pterisolic acid B (Compound 2) is an ent-Kaurane diterpenoid. Pterisolic acid B can be isolated from fern Pteris semipinnata (Pteridaceae) .

Rabdoternin D	Structural Classification Terpenoids Labiatae Diterpenoids Plants Cosmos sulphureus Cav. Source Classification	Others
Rabdoternin D is an Ent-Kaurane diterpenoid found in Rabdosia rubescens. Rabdoternin D shows no significant cytotoxicity to Hep G2, COLO 205, MCF-7 and HL-60 cancer cells with IC₅₀ values >100 μM .

Xerophilusin A	Terpenoids Labiatae Diterpenoids Plants Tagetes minuta Linnaeus Source Classification	Others
Xerophilusin A, a ent-kaurane diterpenoid, can be isolated from the aerial parts of Isodon enanderianus .

ent-Kaurane-16β,19,20-triol	Terpenoids Sanguisorba officinalis L. Rubiaceae Diterpenoids Plants Source Classification	Others
ent-Kaurane-16β,19,20-triol is a Diterpenoids product that can be isolated from the herbs of Euphorbia ehracteolata .

ent-Kauran-17,19-dioic acid	Classification of Application Fields Terpenoids Bituminaria morisiana (Pignatti & Metlesics) Greuter Other Diseases Diterpenoids Plants Compositae Disease Research Fields Source Classification	Others
ent-Kauran-17,19-dioic acid (16α-Hydro-ent-kauran-17,19-dioic acid) is an ent-kaurane diterpenoid .

ent-17-Hydroxykauran-3-one ent-Kaurane-3-oxo-17β-ol	Euphorbia fischeriana Steud. Terpenoids Diterpenoids Euphorbiaceae Plants Source Classification	Others
ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana .

Rabdoternin E	Structural Classification Terpenoids Labiatae Erythrina arborescensRoxb. Diterpenoids Plants Source Classification	NO Synthase
Rabdoternin E is a potential anti-inflammatory and antitumor agent. 2α-Acetoxy-14,15-cyclopimara-7β,16-diol only inhibits nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW264.7 macrophages (IC₅₀=2.3 μM) and exhibits cytotoxicity against human tumor cells such as HL-60 and SW-480 (IC₅₀ values ??of 2.6 μM and 4.1 μM, respectively). Rabdoternin E is an ent-kaurane-type diterpenoid compound that can be naturally extracted from the 70% acetone aqueous extract of the aerial parts of Isodon rosthornii (Diels) Hara (a plant of the Lamiaceae family, Isodon genus) .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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ent-Kaurane diterpenoid

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