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Cat. No.: HY-N11049

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Xerophilusin A

Xerophilusin A, a ent-kaurane diterpenoid, can be isolated from the aerial parts of Isodon enanderianus.

For research use only. We do not sell to patients.

CAS No.: 272459-37-7
Formula: C₂₂H₂₈O₇
Molecular Weight:404.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

Xerophilusin A Chemical Structure

CAS No.: 272459-37-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Xerophilusin A, a ent-kaurane diterpenoid, can be isolated from the aerial parts of Isodon enanderianus^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>10 μM Compound: 30	Cytotoxicity against human HepG2 cells after 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs	[PMID: 17665952]
HL-60	IC₅₀	0.45 μg/mL Compound: 1, xerophilusin A	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 10843567]
K562	IC₅₀	1.6 μM Compound: 30	Cytotoxicity against human K562 cells after 48 hrs Cytotoxicity against human K562 cells after 48 hrs	[PMID: 17665952]
K562	IC₅₀	2.22 μg/mL Compound: 1, xerophilusin A	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 10843567]
MKN-28	IC₅₀	0.12 μg/mL Compound: 1, xerophilusin A	Cytotoxicity against human MKN28 cells after 48 hrs by MTT assay Cytotoxicity against human MKN28 cells after 48 hrs by MTT assay	[PMID: 10843567]
MKN-45	IC₅₀	>10 μM Compound: 30	Cytotoxicity against human MKN45 cells after 48 hrs Cytotoxicity against human MKN45 cells after 48 hrs	[PMID: 17665952]
RAW264.7	IC₅₀	0.6 μM Compound: 1	Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitrite accumulation after 24 hrs by Griess reagent method Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitrite accumulation after 24 hrs by Griess reagent method	[PMID: 19719246]
RAW264.7	IC₅₀	1.8 μM Compound: 1	Inhibition of NF-kappaB activation in LPS-stimulated mouse RAW264.7 cells assessed as relative luciferase activity after 24 hrs by dual reporter gene assay Inhibition of NF-kappaB activation in LPS-stimulated mouse RAW264.7 cells assessed as relative luciferase activity after 24 hrs by dual reporter gene assay	[PMID: 19719246]
RAW264.7	IC₅₀	11.3 μM Compound: 1	Cytotoxicity against mouse RAW264.7 cells after 24 hrs by MTT assay Cytotoxicity against mouse RAW264.7 cells after 24 hrs by MTT assay	[PMID: 19719246]

Chemical Information

CAS No. 272459-37-7
Molecular Weight 404.45
Formula C₂₂H₂₈O₇
SMILES

O[C@@]12[C@]34[C@]5([H])[C@]6([C@](C(C)(CCC6)C)([H])[C@@H]2O)[C@@](O1)([H])O[C@@]3([H])[C@](C[C@H]5OC(C)=O)([H])C(C4=O)=C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (281 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Na Z, et al. Diterpenoids from Isodon enanderianus. Phytochemistry, 2002, 60(1): 55-60.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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