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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

fungal cell wall biosynthesis

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By Targets:	Fungal (9) Androgen Receptor (3) Antibiotic (3) Bacterial (1) Endogenous Metabolite (3) Environmental Pollutants (2) Isotope-Labeled Compounds (1) Parasite (3) Reference Standards (1)
By Research Areas:	Infection (10) Metabolic Disease (1)

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Natural
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Isotope-Labeled Compounds

Targets Recommended: Fungal Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor BCL6 Tim3 VISTA BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0848

Tricyclazole 2 Publications Verification	Environmental Pollutants Bacterial	Infection Metabolic Disease
Tricyclazole is a pentaketone melanin biosynthesis inhibitor and a unique fungicide for controlling rice blast. Tricyclazole alters the structure and function of fungal cell walls, reduces fungal pathogenicity and penetration, and causes dose-dependent liver damage in animals .

HY-B0846

Dimethomorph	Environmental Pollutants Fungal Androgen Receptor Parasite	Infection
Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC₂₀ of 0.263 µM .

HY-125723

Echinocandin B SL 7810; A-30912 A	Endogenous Metabolite Fungal Antibiotic	Infection
Echinocandin B (SL 7810) is a lipopeptide antifungal antibiotic. Echinocandin B is produced by Aspergillus nidulans. Echinocandin B inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B exhibits activity against a variety of Aspergillus species .

HY-B1838A

Asulam potassium	Fungal	Infection
Asulam (potassium salt) is a chitin synthase inhibitor against plant pathogenic fungi. Asulam (potassium salt) interferes with the biosynthesis of chitin in the fungal cell wall to destroy the integrity and normal growth and reproduction of fungal cells, thereby exerting bacteriostatic activity. Asulam (potassium salt) is promising for research of fungal diseases such as downy mildew and gray mold in spinach, tulips, daffodils and lilies .

HY-B0846S

Dimethomorph-d8	Fungal Androgen Receptor Parasite	Infection
Dimethomorph-d₈ is the deuterium labeled Dimethomorph . Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 μM .

HY-B0846R

Dimethomorph (Standard)	Reference Standards Fungal Androgen Receptor Parasite	Infection
Dimethomorph (Standard) is the analytical standard of Dimethomorph. This product is intended for research and analytical applications. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM .

HY-125723B

Echinocandin B (purity>65%) SL 7810 (purity>65%); A-30912 A (purity>65%)	Antibiotic Fungal Endogenous Metabolite	Infection
Echinocandin B (purity>65%) (SL 7810 (purity>65%)) is a lipopeptide antifungal antibiotic. Echinocandin B (purity>65%) is produced by Aspergillus nidulans. Echinocandin B (purity>65%) inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>65%) exhibits activity against a variety of Aspergillus species .

HY-125723A

Echinocandin B (purity>85%) SL 7810 (purity>85%); A-30912 A (purity>85%)	Antibiotic Fungal Endogenous Metabolite	Infection
Echinocandin B (purity>85%) (SL 7810 (purity>85%)) is a lipopeptide antifungal antibiotic. Echinocandin B (purity>85%) is produced by Aspergillus nidulans. Echinocandin B (purity>85%) inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>85%) exhibits activity against a variety of Aspergillus species .

HY-17579S

Micafungin-d11 ammonium FK463-d₁₁ ammonium	Isotope-Labeled Compounds Fungal	Infection
Micafungin-d₁₁ ammonium (FK463-d₁₁ ammonium) is the deuterium labeled Micafungin ammonium. Micafungin (FK463) is an antifungal agent and can inhibit β-1,3-glucan synthase. Micafungin inhibits 1,3-β-glucan biosynthesis in fungal cell walls. Micafungin can be used for the research of fungal infection, such as candida infections and aspergillosis .

HY-119726B

Fosmanogepix TFA	Fungal	Infection
Fosmanogepix TFA (APX001 TFA) is an orally active APX001A (HY-18233) prodrug and antifungal agent. Fosmanogepix TFA is effective against Cryptococcus neoformans, Fluconazole (HY-B0101)-resistant C. auris. Fosmanogepix TFA is effective in the treatment of invasive pulmonary aspergillosis and pulmonary murine mucormycosis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125723

Echinocandin B SL 7810; A-30912 A	Structural Classification Monophenols Microorganisms Phenols Source Classification	Endogenous Metabolite Fungal Antibiotic
Echinocandin B (SL 7810) is a lipopeptide antifungal antibiotic. Echinocandin B is produced by Aspergillus nidulans. Echinocandin B inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B exhibits activity against a variety of Aspergillus species .

HY-125723B

Echinocandin B (purity>65%) SL 7810 (purity>65%); A-30912 A (purity>65%)	Structural Classification Monophenols Microorganisms Phenols Source Classification	Antibiotic Fungal Endogenous Metabolite
Echinocandin B (purity>65%) (SL 7810 (purity>65%)) is a lipopeptide antifungal antibiotic. Echinocandin B (purity>65%) is produced by Aspergillus nidulans. Echinocandin B (purity>65%) inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>65%) exhibits activity against a variety of Aspergillus species .

HY-125723A

Echinocandin B (purity>85%) SL 7810 (purity>85%); A-30912 A (purity>85%)	Structural Classification Monophenols Microorganisms Phenols Source Classification	Antibiotic Fungal Endogenous Metabolite
Echinocandin B (purity>85%) (SL 7810 (purity>85%)) is a lipopeptide antifungal antibiotic. Echinocandin B (purity>85%) is produced by Aspergillus nidulans. Echinocandin B (purity>85%) inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>85%) exhibits activity against a variety of Aspergillus species .

Cat. No.	Product Name	Chemical Structure

HY-B0846S

Dimethomorph-d8
Dimethomorph-d₈ is the deuterium labeled Dimethomorph . Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 μM .

HY-17579S

Micafungin-d11 ammonium
Micafungin-d₁₁ ammonium (FK463-d₁₁ ammonium) is the deuterium labeled Micafungin ammonium. Micafungin (FK463) is an antifungal agent and can inhibit β-1,3-glucan synthase. Micafungin inhibits 1,3-β-glucan biosynthesis in fungal cell walls. Micafungin can be used for the research of fungal infection, such as candida infections and aspergillosis .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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fungal cell wall biosynthesis

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
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